Trulance (Plecanatide) from Maple Leaf Medications.

Prescription Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Trulance 3mg 30 $167.00 Add To Cart
Trulance 3mg 90 $470.00 Add To Cart
Dosage: 3mg
Quantity: 30
Price: $167.00
Dosage: 3mg
Quantity: 90
Price: $470.00

What is Trulance used for?

With the generic name Plecanatide, this medication is an oral tablet used to treat Chronic Idiopathic Constipation or CIC. It also treats irritable bowel syndrome (IBS) with constipation.

This is available in Trulance 3 mg tablet forms.

How to Use Trulance?

Always read and understand the patient information leaflet that comes with your prescription medication. Avoid taking any products without fully understanding all their instructions and cautions. If you have queries, you consult a medical professional.

Take your Plecanatide tablet orally. This is usually prescribed once daily or as needed on the advice of your physician. You may take it with/without a meal/snack. Swallow the tablet whole and drink water afterward. 

Make sure to take this prescription medication consistently and exactly as prescribed. Create a dosing schedule to avoid missing your doses. Do not change your Trulance dosage without the advice of your doctor. Also, do not stop taking this oral tablet abruptly or even for a few days to avoid worsening conditions.

Trulance Side Effects

Common Side Effects: 

  • Diarrhea 
  • Abdominal pain 

The majority of the adverse reactions caused by this oral drug are mild and temporary. If they worsen or persist, notify your healthcare provider.  

Serious adverse effects like: 

  • Severe diarrhea 
  • Severe abdominal pain 
  • Dehydration 

Precautions when using Trulance

Before you take Plecanatide, you should talk to your physician regarding your medical history. This prescription medication may not be suitable for patients with stomach or intestinal blockage history. Further, you should also discuss all prescription drugs, OTC drugs, herbal products, and food supplements you take because of possible interactions with this medication.

Pay close attention to any allergic reaction that you may experience while on this medication. Do not take this oral tablet if you have an allergy to Plecanatide or any of the inactive ingredients it may contain. Discontinue medication and seek emergency help once you notice signs of severe hypersensitivity.

Pregnant and nursing moms should talk to their doctors and discuss all the risks before using this prescription drug. 

How much does Trulance cost in Canada?

You may check this oral tablet’s price list on this page. allows you to purchase prescription and nonprescription medications 24/7 to serve your health needs.   

Frequently Asked Questions

How long after taking Trulance will I have a bowel movement? 

This oral tablet is supposed to relieve constipation after a week of treatment. If it does not work after a week, you must talk to your healthcare provider about it.

How does Trulance work? 

This Guanylate Cyclase-C Agonist works by elevating the concentrations of Cyclic Guanosine Monophosphate (cGMP), which stimulates the secretion of bicarbonate & chloride into the intestines. This leads to an increase in gastrointestinal fluid and acceleration of transit.

Should I take Trulance medication in the morning or at night? 

You may take this prescription tablet any time of the day as long as you follow a dosing schedule. It works best if administered at the same time each day.

Does Trulance diarrhea go away? 

Mild diarrhea usually happens after four weeks of taking this oral drug. Usually, this side effect does not persist and will eventually go away.

Which is stronger, Trulance vs Linzess? 

These products are indicated for chronic constipation and are equally effective. They are also both classified as Guanylate Cyclase-C Agonists.

Is there a generic for this medication? 

There are still no available alternatives to this brand-name medication. Also, you must not take other products aside from what was prescribed by your physician without consulting them to avoid adverse interactions. 

If you have any questions regarding medication or basic inquiries about be sure to contact us in writing. Or, if you need to speak to a live representative, you can call our toll-free number at 1-800-998-4016, Monday to Friday, 6 am to 6 pm, and Saturdays from 7 am to 4 pm.
Maple Leaf Medications is accredited by the Canadian International Pharmacy Association (CIPA). We partner with licensed pharmacies in Canada and other countries to provide you with medication choices and affordable drug prices.


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Quantities Available:

30, 90



Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Trulance (Plecanatide). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Trulance (Plecanatide).