Rybelsus (Semaglutide) from Maple Leaf Medications.

Prescription Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Rybelsus 3mg 30 $236.00 Add To Cart
Rybelsus 3mg 90 $677.00 Add To Cart
Rybelsus 7mg 30 $250.00 Add To Cart
Rybelsus 7mg 90 $719.00 Add To Cart
Rybelsus 14mg 30 $341.75 Add To Cart
Rybelsus 14mg 90 $995.00 Add To Cart
Dosage: 3mg
Quantity: 30
Price: $236.00
Dosage: 3mg
Quantity: 90
Price: $677.00
Dosage: 7mg
Quantity: 30
Price: $250.00
Dosage: 7mg
Quantity: 90
Price: $719.00
Dosage: 14mg
Quantity: 30
Price: $341.75
Dosage: 14mg
Quantity: 90
Price: $995.00

What is Rybelsus?

Rybelsus, with the generic name semaglutide, is an oral medication indicated to improve glycemic control together with proper diet and regular exercise in people with type 2 diabetes mellitus. By controlling the blood sugar level, it could help prevent heart attack, stroke, kidney damage, nerve problems, vision loss, loss of limbs, and sexual function problems.

This is available in Rybelsus 3 mg, 7 mg, and 14 mg tablet forms.

How does Rybelsus work?

This glucagon-like peptide-1 agonist works in a glucose-dependent manner by stimulating insulin secretion and lowering glucagon secretion. It is also responsible for the minor delay in gastric emptying in the early postprandial phase.

How to use

To begin, read the medication information leaflet that comes with this product. Do not take this tablet unless you fully understand the drug information and instructions in the guide. If you need further medical advice or have questions on this treatment, ask your doctor or pharmacist.

Take this anti-diabetic medication orally. It should be taken at least thirty minutes before eating, drinking, or taking other oral drugs. Swallow the tablet whole. Avoid cutting, chewing, or crushing it. Drink half a cup or 120 mL of water afterward. Do not take rybelsus with any other beverage aside from water.

Remember to take this oral drug regularly and with a dosing schedule to achieve the best results. This is usually prescribed once daily. Your dosage and frequency will depend on your medical condition, response to treatment, and other medications you are taking. Do not alter your dosing or stop taking this drug abruptly to avoid worsening conditions.

Rybelsus Side Effects


  • Nausea
  • Vomiting
  • Abdominal discomfort
  • Diarrhea
  • Constipation
  • Loss of appetite

Most of these side effects brought about are mild and short-term. If any of the adverse reactions persist or worsen, contact your physician or any healthcare professional. You also have to report severe side effects, including:

  • Signs of kidney problems (change in urinary output, dark urine)
  • Symptoms of pancreatitis (severe abdominal pain, persistent vomiting, nausea)
  • Hyperglycemia or high blood sugar
  • Hypoglycemia or low blood sugar
  • Vision changes

These are not a comprehensive list of side effects.

Rybelsus and Alcohol

Limit alcohol intake because these two might interact. It could cause low blood sugar and worsen side effects such as blurred vision, drowsiness, and dizziness. You also have to practice extreme caution when doing activities that require alertness and clear vision, like driving and using machinery.

Other Precautions

Before taking this anti-diabetic drug, you have to disclose your full medical history to your physician. This includes any history of pancreatitis, diabetic retinopathy, GI disorders, or kidney problems. Some diseases or disorders may impact how you will respond to rybelsus. You also have to tell your doctor about all the supplements, herbal medicines, prescription drugs, and nonprescription drugs you take, as they may have drug interactions with semaglutide.

Constantly look out for signs of an allergic reaction while on this treatment. Do not take this oral drug if you have a known allergy to semaglutide or any inactive ingredients each tablet may contain. You have to alert the medical emergency line once you observe signs of hypersensitivity such as swelling of the face and neck, skin rashes, severe dizziness, hives, and breathing trouble.

Tell your doctor immediately if you are pregnant or trying to get pregnant. Pregnancy could worsen or cause diabetes. It may be necessary to change your anti-diabetic medication because rybelsus is not recommended for pregnant women.

Frequently Asked Questions

When is the best time to take this medication?

It is best to take this medication in the morning, 30 minutes to 1 hour before breakfast.

Can this medication cause weight loss?

There is no direct link between Rybelsus & weight loss, although some patients reported weight loss while on this medication.

What is the difference between Rybelsus and Metformin?

On Rybelsus vs Metformin, both are anti-diabetic drugs. While the latter could be taken with food, the former should be strictly taken on an empty stomach.

What is the difference between Rybelsus and Ozempic?

On Rybelsus vs Ozempic, both are semaglutide, but Rybelsus is available in tablet forms while Ozempic is available in subcutaneous injections.

Can I purchase this medication online?

You may purchase this medication online if you have a valid prescription.\

If you have any questions regarding medication or basic inquiries about MapleLeafMeds.com be sure to contact us in writing. Or, if you need to speak to a live representative, you can call our toll-free number at 1-800-998-4016, Monday to Friday, 6 am to 6 pm, and Saturdays from 7 am to 4 pm.
Maple Leaf Medications is accredited by the Canadian International Pharmacy Association (CIPA). We partner with licensed pharmacies in Canada and other countries to provide you with medication choices and affordable drug prices.

Brand Name:


Scientific Name:


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3mg, 7mg, 14mg

Quantities Available:

30, 90



Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Rybelsus (Semaglutide). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Rybelsus (Semaglutide).