Rybelsus (Semaglutide) from Maple Leaf Medications.

Rybelsus (semaglutide) Indications

Rybelsus, generic name semaglutide, is an oral prescription used to improve the blood sugar of people with type 2 diabetes mellitus (T2DM). This medication is used in conjunction with proper diet and exercise.

Rybelsus is not approved for the first line treatment in people with T2DM and is not approved for use in those with type 1 diabetes mellitus or diabetic ketoacidosis.

Rybelsus is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist. It acts by stimulating the secretion of insulin and lowers glucagon secretion in a glucose-dependent mechanism. It also slows down gastric emptying in the early phase after a meal, which also helps lower the blood glucose level.

Rybelsus (semaglutide) Uses and Dosage

Make sure to read the medication guide before using Rybelsus for the first time.

Take Rybelsus exactly as prescribed. Rybelsus is taken by mouth once daily (preferably in the morning) with water and on an empty stomach. Do not take Rybelsus with any other beverages. Avoid drinking anything besides plain water or eating for at least 30 minutes after taking the medication. Do not discontinue Rybelsus without your doctor’s approval.

Rybelsus (semaglutide) Side Effects

Common side effects of Rybelsus may include:

• Abdominal pain
• Stomach upset
• Nausea
• Vomiting
• Loss of appetite
• Constipation
• Diarrhea

These side effects are usually mile, yet if any become unmanageable seek the help of your healthcare provider.

Serious Side Effects

Severe side effects of Rybelsus may include:

• Changes in the amount of urine
• Vision changes
• Severe abdominal pain
• Persistent nausea and vomiting
• Low blood sugar
• High blood sugar

These severe adverse reactions should be reported to your doctor immediately.

Allergic Reactions

Do not take Rybelsus if you have an allergy to semaglutide or any other ingredients in this medication. Seek emergency intervention if an allergy develops while using this prescription medication. Signs of an allergy include:

• Itching
• Rashes
• Hives
• Swelling of the face and the neck area
• Swollen lymph nodes
• Severe dizziness
• Difficulty breathing
• Wheezing

Rybelsus (semaglutide) Cautions

Rybelsus may not be recommended for people with:

• Pancreatitis
• Diabetic retinopathy
• Gastrointestinal disorders
• Kidney problems
• Gallbladder disease

Rybelsus diabetes medication should not be used during pregnancy. As pregnancy can make diabetes worse, consult your doctor regarding changes to your treatment plan should you become pregnant.

It is unknown if Rybelsus can be excreted through breast milk. Therefore, consult your doctor before taking Rybelsus if you are or plan to breastfeed.

Rybelsus (semaglutide) Form and Strength

Rybelsus is available as:

• Rybelsus, tablets
  • 3 mg
  • 7 mg
  • 14 mg

FAQ

Is Rybelsus like metformin?

Rybelsus and metformin are used to help improve the glycemic control of people with type 2 diabetes mellitus. Metformin is considered a first line of treatment, whereas Rybelsus should only be given if other diabetes treatments are not effective.

How long can you take Rybelsus?

Rybelsus is safe for long-term use. Currently there are patients with type 2 diabetes that have been taking Rybelsus since 2017.

When is the best time of the day to take Rybelsus?

Rybelsus is best taken in the morning upon waking. It should be administered on an empty stomach and at least 30 minutes before eating.

Can you drink alcohol with Rybelsus?

Alcohol should be avoided while taking Rybelsus. Beverages that contain alcohol can increase the risk of developing hypoglycemia.

Resources

https://www.rybelsus.com/

https://www.webmd.com/drugs/2/drug-178019/rybelsus-oral/details

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/213051s000lbl.pdf

https://reference.medscape.com/drug/ozempic-rybelsus-wegovy-semaglutide-1000174

https://www.rxlist.com/rybelsus-side-effects-drug-center.htm