Janumet (Sitagliptin/Metformin) from Maple Leaf Medications.

Prescription Prescription Required
Formulation : Film Coated Tablet
Drug Name Dosage Quantity Price Buy Now
Janumet 50/500mg 56 $51.00 Add To Cart
Janumet 50/500mg 112 $87.00 Add To Cart
Janumet 50/850mg 56 $75.95 Add To Cart
Janumet 50/850mg 112 $129.70 Add To Cart
Janumet 50/850mg 168 $189.60 Add To Cart
Janumet 50/1000mg 56 $49.00 Add To Cart
Janumet 50/1000mg 112 $90.00 Add To Cart
Dosage: 50/500mg
Quantity: 56
Price: $51.00
Dosage: 50/500mg
Quantity: 112
Price: $87.00
Dosage: 50/850mg
Quantity: 56
Price: $75.95
Dosage: 50/850mg
Quantity: 112
Price: $129.70
Dosage: 50/850mg
Quantity: 168
Price: $189.60
Dosage: 50/1000mg
Quantity: 56
Price: $49.00
Dosage: 50/1000mg
Quantity: 112
Price: $90.00

( Affordable Generic Alternatives )

Buy Sitagliptin/Metformin Sitagliptin/Metformin

Prescription Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Sitagliptin/Metformin 50/1000mg 100 $152.00 Add To Cart
Dosage: 50/1000mg
Quantity: 100
Price: $152.00

What is Janumet? 

Janumet, with the generic name sitagliptin and metformin HCl, is an oral drug indicated to improve glycemic control for people with type 2 diabetes mellitus. This antidiabetic is an adjunct to proper diet, regular exercise, and other medications. By controlling high blood sugar levels, it helps prevent complications of diabetes mellitus, such as stroke, heart failure, kidney damage, nerve problems, blindness, loss of limbs, and sexual dysfunction. 

This drug is a combination of a dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide. It works by slowing down the inactivation of incretin hormones and improving glucose tolerance. This is available in Janumet 50/1000 mg and Janumet 50 500 mg. 

How to use Janumet 

To begin, read the medication guide or information leaflet that comes with this medication. Never take this medication if you have not fully understood all the information and instructions in the guide. If you need further medical advice or have queries on this treatment, ask your doctor or pharmacist. 

Take this antihyperglycemic orally. This is usually prescribed twice a day or BID, with meals. Swallow this medication and take it with plenty of water. It is not recommended to cut, chew or crush this tablet. 

Remember to take this drug regularly and with a dosing schedule for optimum results. Follow your doctor’s instructions carefully. Your Janumet dosage and frequency will depend on your medical condition, response to treatment, and other medications you are taking. Do not change your dosing or stop taking this drug abruptly to avoid worsening conditions. 

Keep in mind that this medication is only a part of a treatment plan. It is necessary to continue taking your other medications and stick to a healthy diet and regular exercise to achieve the best results. 

Side effects  

Common side effects of Janumet: 

  • Nausea 
  • Dizziness 
  • Headache 
  • Vomiting 
  • Metallic taste in the mouth 
  • Fatigue or weakness 
  • Constipation 
  • Diarrhea 
  • Stomach upset 
  • Muscle pain 
  • Joint pain 

For the most part, the side effects brought about by this diabetic medication are mild and will disappear in a few days. In case the adverse effects persist or worsen, call your doctor or any healthcare provider. It is essential to look out for severe side effects, including: 

  • Signs of lactic acidosis (stomach symptoms that return or occur after the first days of treatment) 
  • Signs of hypoglycemia (sudden sweating, blurred vision, shaking, fast heartbeat, dizziness, tingling of the hands and feet) 
  • Signs of hyperglycemia (thirst, confusion, increased urination, fruity breath odor) 
  • Shortness of breath 
  • Change in urine output 
  • Unusual skin blisters 
  • Sudden weight gain 
  • Persistent vomiting 
  • Severe stomach pain 
  • Loss of appetite 

This is not a full or complete list of Janumet’s side effects. 


Before taking this oral medication, it is necessary to disclose your medical history to your physician, especially severe breathing problems (COPD, asthma), blood problems, pancreatitis, liver problems, kidney problems, and gallstones. Some medical conditions and diseases may affect how your body will respond to the medication. Additionally, talk about all the prescription and nonprescription drugs you are taking, as they may have drug interactions with sitagliptin or metformin. 

Watch out for some signs and symptoms of an allergic reaction while on this treatment. Never take this drug if you have a known allergy to sitagliptin, metformin, or any inactive ingredients each tablet may contain. Signs of hypersensitivity reaction are skin rashes, severe dizziness, swelling of the face, hives, and trouble breathing. Once you notice these signs, discontinue medication and seek emergency management. 

Taking diuretics or water pills, profuse sweating, high fever, vomiting, and diarrhea may cause dehydration, leading to lactic acidosis. To avoid this, stay hydrated and avoid taking diuretics. 

Pregnancy may cause or worsen diabetes. Consult your doctor right away if you are pregnant, as this may warrant changes in your treatment plan. 

The metformin component of this drug promotes ovulation. That said, it could cause changes in the menstrual cycle and increase the risk of getting pregnant. Consult your doctor if you opt to use any birth control method. 


Frequently Asked Questions 

Is this medication safe? 

Clinical trials have proven that this antidiabetic drug is safe and effective. 

How long does it take for Janumet to work? 

This drug starts working within 5 days of regular use. 

What is the difference between Janumet and Janumet XR? 

Janumet XR is an extended-release version of Janumet that is only taken once a day. 

Does this medication cause weight gain? 

An increase in weight is a rare adverse effect of this medication. Consult your doctor if you notice sudden and unusual weight gain while taking this drug. 

How much does this medication cost? 

You may check the pricing of this product by clicking here.

Brand Name:


Scientific Name:


Other Names:

Janumet, Sitacip M


50/500mg, 50/850mg, 50/1000mg

Quantities Available:

56, 100, 112, 168


Film Coated Tablet, Tablet

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Janumet (Sitagliptin/Metformin). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Janumet (Sitagliptin/Metformin).

Similar Products