Anusol HC Ointment (Hydrocortisone Acetate/Zinc Sulfate) from Maple Leaf Medications.

What is Anusol HC Ointment used for?

Anusol HC, with the generic name hydrocortisone acetate and zinc sulfate, is a topical ointment prescribed to relieve and help treat hemorrhoids. It lessens symptoms such as swelling, itching, and irritation. It can also be prescribed to alleviate discomfort following surgery in the anal area and for other conditions affecting the anal area. This is classified as a topical corticosteroid.

This topical drug may be used for other indications not mentioned above, provided that it is prescribed by a medical doctor.

How does Anusol HC Ointment work?

This ointment is a combination of hydrocortisone and zinc sulfate. This is known to have anti-inflammatory, vasoconstrictive, and antipruritic effects. It suppresses the migration of polymorphonuclear leukocytes or PMN while reversing increased capillary permeability.

Anusol HC Ointment – How to Use

Before using Anusol HC Ointment, you must always read the medication guide, especially if using it for the first time. Do not use this medication without fully understanding all the necessary information provided. You may consult your physician or a pharmacist to know more about this product.

This ointment is usually used around two to four times daily or after each bowel movement. Prior to applying this topical product, make sure that the anal area is clean and dry. If applying it inside the anus, use the applicator that it comes with. Fill the applicator with ointment and carefully insert the tip just about ½ to 1 inch inside the anus. Apply the medication in and around the area. If it should only be applied outside the anus, use the finger to administer a small amount of ointment. Then, gently rub it in. Do not change the prescribed Anusol HC Ointment dosage, and avoid applying this product more frequently than required.

Anusol HC Ointment Side Effects

Common side effects:

  • Mild burning in the anal area 
  • Temporary itching 
  • Redness 

These common side effects caused by the ointment are supposed to be mild and temporary. In case they aggravate or do not resolve in a few days, you should talk to your physician. You must also report severe adverse reactions, including: 

  • Change in skin appearance of the anal area 
  • Rectal bleeding 
  • Severe swelling 
  • Pus 
  • Fever
  • Chills
  • Unusual tiredness
  • Headache
  • Weight loss
  • Increased thirst and urination
  • Vision problems

Precautions when using Anusol HC Ointment

Using Anusol HC may be contraindicated for people with certain conditions. Tell your doctor if you have any history of gastrointestinal conditions, liver problems, diabetes, or recent infections. You must also discuss the medications you are using with your physician because they may interact with this drug.

You should not use this ointment if you have a known hypersensitivity to hydrocortisone, zinc sulfate, or any of this drug’s contents. Signs of severe hypersensitivity are itching with/without hives, severe dizziness, swelling of the face, and trouble breathing. If this occurs, you must immediately seek emergency medical help.

Pregnant and lactating moms must take caution when using this topical drug as it is unknown if it can cause harm to fetuses and nursing babies. Use this type of medication only if strongly advised by the doctor.

How much does Anusol HC Ointment cost in Canada?

You may check the Anusol HC Ointment price from the information reflected above. is an online Canadian pharmacy that offers authentic prescription and nonprescription drugs at their lowest price.

Frequently Asked Questions

What is the difference between Anusol and Anusol HC? 

Unlike the HC variant, Anusol does not contain hydrocortisone acetate. Hydrocortisone is a corticosteroid that helps relieve swelling or inflammation.

How long can I use Anusol HC Ointment? 

This prescription medication is usually prescribed for seven days. Do not use this product longer than prescribed unless your doctor advises you to restart or continue using this medication.

Does Anusol HC Ointment relieve pain? 

As this type of drug helps relieve inflammation, it can also relieve pain and discomfort. This ointment also works as an antiseptic and astringent.

How quickly does Anusol HC Ointment work? 

For most people, their hemorrhoids begin to heal after a week or two. It is important to apply this drug exactly as instructed to achieve the best results.

Can I use Anusol HC Ointment more than four times a day? 

You should not use this topical corticosteroid more than four times in 24 hours. Using this ointment more frequently than recommended can increase the risk of severe undesirable effects.

What is better, Anusol HC Ointment or Cream? 

These products contain the same active ingredients. The ointment is thicker and better for relieving sores and dry skin. The cream is usually preferred if the medication will be rubbed in because it has a thinner consistency.

Can you buy Anusol HC Ointment over the counter? 

You should have a prescription when purchasing this ointment in traditional drug stores or online pharmacies. The prescription should be made by a medical physician or any licensed medical professional. 

Brand Name:

Anusol HC Ointment

Scientific Name:

Hydrocortisone Acetate/Zinc Sulfate

Other Names:

Anodan HC, Anusol HC Ointment


0.5/0.5%, noDose

Quantities Available:

1, 30g



Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Anusol HC Ointment (Hydrocortisone Acetate/Zinc Sulfate). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Anusol HC Ointment (Hydrocortisone Acetate/Zinc Sulfate).

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