Glyxambi (Empagliflozin/Linagliptin) from Maple Leaf Medications.

What is Glyxambi used for?

Glyxambi, with the generic name empagliflozin and linagliptin, is an oral medication indicated to enhance glycemic control, together with proper diet and exercise, in adults with type 2 diabetes mellitus.

This is also used to reduce the risk of cardiovascular death and prevent complications such as blindness, nerve problems, kidney damage, loss of limbs, and sexual dysfunction.

This is available in Glyxambi 25 mg/5mg and 10mg/5mg tablet forms.

How does Glyxambi work?

The drug Glyxambi was developed as a combination of sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitor.

It works by reducing the renal reabsorption of filtered glucose and lowering its renal threshold, which increases the excretion of glucose through the urine. It could also release insulin in a glucose-dependent manner and decrease glucagon levels in the system.

How to use Glyxambi?

Read the medicine information booklet that comes with this product first. Do not use this tablet if you have not fully understood all the drug information in the printed guide. If you have questions about this treatment or need further medical advice, do not hesitate to ask your doctor or pharmacist.

Take this tablet orally. It may be taken with or without food or as prescribed by your doctor. Swallow Glyxambi and drink a glass of water. It is not recommended to split, chew, or crush Glyxambi. This is usually prescribed once daily, in the morning.

Remember to take this oral drug regularly and with a dosing schedule for the best results. Follow the exact directions as per your doctor. Your Glyxambi dosage will depend on your response to treatment. To avoid worsening symptoms, do not change your dose or stop using this medicine abruptly.

Because this medication is only a part of a treatment plan, it is just as important to comply with the diet and work out the recommendations of your doctor. Stick to a well-balanced diet and regular exercise to get the best out of this medication.

Glyxambi Side effects

Common side effects:

• Nausea
• Dizziness
• Lightheadedness
• Frequent urination
• Stomach upset

For the most part, the side effects caused by Glyxambi are mild and temporary. If the adverse reactions get worse to take a long time to resolve, you have to call your doctor or any healthcare professional. You also have to report any severe side effects, like:

• Signs of urinary tract infection (painful/difficult urination, bloody urine, fever)
• Signs of pancreatic disease (persistent vomiting, severe abdominal pain which radiates to the back)
• Signs of heart failure (shortness of breath, swelling of the extremities, sudden weight gain)
• Change in urinary output
• Joint pain
• Unusual skin blisters
• Unusual tiredness
• Trouble breathing
• Signs of a yeast infection (unusual discharge and itching of vagina or penis)
• Low blood sugar
• High blood sugar
• Dehydration

This is not an exhaustive list of Glyxambi side effects.

Precautions when using Glyxambi

Before using this maintenance drug, make sure to fully disclose your medical history to your physician. This includes any history of pancreatitis, kidney disease, gallstones, hypotension, heart failure, high cholesterol, heart disease, yeast infection, or alcohol abuse. Certain diseases and disorders may directly affect how your body will respond to this medication. You also have to tell your physician about all the prescription drugs, nonprescription drugs, supplements, and herbal products you are taking as they may have drug interactions with this antidiabetic.

Be watchful for signs of an allergic reaction while on this treatment. Do not take this oral medication if you have a known allergy to empagliflozin, linagliptin, or any inactive ingredients each tablet may contain. It is important to seek emergency medical management if you encounter signs of hypersensitivity, such as breathing trouble, swelling of the face and neck, hives, severe dizziness, and skin rash.

Limit or avoid drinking alcoholic beverages while on this medication. Alcohol could cause hypoglycemia and high ketone level. It could also worsen side effects, such as blurred vision, dizziness, and drowsiness. In addition, you also have to practice safety precautions when doing activities that require alertness, like using machinery or driving.

Since pregnancy could worsen diabetes, tell your doctor right away if you are pregnant or planning to get pregnant. This condition might warrant changes in your diabetes treatment.

Frequently Asked Questions

Is Glyxambi medication safe?

This medication is safe and effective in lowering blood sugar levels.

How is this medication classified?

Glyxambi drug class is SGLT2 inhibitor and DPP-4 inhibitor.

Could this Glyxambi and Metformin be given together?

Yes, this combination is approved by most doctors.

Does Glyxambi cause weight loss?

There is no direct link between Glyxambi & weight loss.

How much does Glyxambi cost?

You may check the pricing of this product by clicking here.