Pentasa (Mesalamine) from Maple Leaf Medications.

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Formulation : Prolonged Release Tablet
Drug Name Dosage Quantity Price Buy Now
Pentasa 500mg 100 $96.00 Add To Cart
Pentasa 500mg 200 $150.00 Add To Cart
Pentasa 500mg 300 $214.00 Add To Cart
Dosage: 500mg
Quantity: 100
Price: $96.00
Dosage: 500mg
Quantity: 200
Price: $150.00
Dosage: 500mg
Quantity: 300
Price: $214.00

Pentasa Uses

Pentasa, with the generic name mesalamine, is an oral medication indicated to treat adult patients with mildly to moderately active ulcerative colitis. It decreases the swelling in the colon and helps reduce symptoms such as abdominal pain, diarrhea, and rectal bleeding.

This is available in 250 mg and 500 mg controlled-release capsules.

How does Pentasa work?

This aminosalicylate works by obstructing the activity of cyclooxygenase and lipoxygenase. Doing so reduces prostaglandin production. Prostaglandin is the compound responsible for the colon’s inflammation, which is the main symptom linked to ulcerative colitis.

How to use Pentasa

To begin, read the medication information booklet included with this medicine. Do not take any prescription drug without fully understanding the drug information and warnings printed in the guide. If you need further medical advice or have queries regarding this treatment, you may ask your doctor or pharmacist.

Take the capsule orally. This is usually prescribed four times daily. You may take the oral medication with or without a meal or as directed by your doctor. Swallow the whole and drink plenty of water right after to avoid kidney stones. Do not split, crush, or chew this controlled-release drug, as this should be properly released in the colon.

Remember to use this medication orally and with a dosing schedule to achieve the best results. Do not change your dosing as it depends on your medical condition and response to treatment. In addition, do not stop taking this aminosalicylate without the advice of your doctor to avoid worsening conditions.

Pentasa Side Effects

Common side effects:

  • Nausea
  • Headache
  • Dizziness
  • Vomiting
  • Stomach cramps
  • Gas
  • Diarrhea
  • Constipation
  • Tiredness

For the most part, the side effects caused by this prescription drug will resolve without intervention and are temporary. If the adverse reactions persist or get worse over time, you may have to hold the medication and consult your doctor or any healthcare provider. Moreover, you must report any severe side effects, including:

  • Increased abdominal cramping
  • Fever
  • Bloody diarrhea
  • Change in urine output
  • Blood in the urine
  • Dark urine
  • Persistent vomiting
  • Yellowish skin
  • Chest pain
  • Shortness of breath

This is not a complete or full list of Pentasa’s side effects.


Before taking this prescription medication, you should disclose your entire medical history with your physician. This includes any history of pyloric stenosis or any stomach blockage, liver disease, and kidney disease. Some conditions may directly impact how your body will respond to this treatment. Furthermore, you should also talk about all the prescription drugs, nonprescription drugs, and herbal products you are taking because of possible drug interactions.

Always lookout for an allergic reaction while taking this medication. Do not take this controlled release drug if you have a known allergy to mesalamine, salicylates, aminosalicylates, or any inactive ingredients it may contain. Signs of hypersensitivity are breathing trouble, severe dizziness, hives, swelling of the face, and skin rashes. Once you start to observe these symptoms, call your medical emergency line.

This drug is similar to aspirin. Those who are eighteen years old and below should not take aspirin or any aspirin-related drugs if suffering from flu, chickenpox, or other undiagnosed illness. Aspirin can elevate the risk of Reye’s syndrome, which is a rare but serious condition.

You could be more sensitive to the sun while on this medication. It could also worsen skin conditions like eczema and atopic dermatitis. Limit your time outdoors. Always wear protective clothing and apply sunblock cream when going out.

Due to the probable harm that this medication could cause, pregnant and breastfeeding moms must avoid this medication. Remember that potential benefits should be greater than the potential risks.

Frequently Asked Questions

Is Pentasa prescribed for Crohn’s disease?

Some studies on Pentasa & Crohn disease have proven that this effectively reduces inflammation and irritation of the intestinal lining.

Does this medica6tion suppress the immune system?

No, this medication is safe and does not affect the immune system.

What is the difference between Pentasa and Asacol?

On Pentasa vs Asacol, the former comes in controlled-release capsules while the latter are in delayed-release tablets.

What is the difference between Pentasa & Lialda?

On Pentasa vs Lialda, both are mesalamine and are effective in treating ulcerative colitis.

How much does Pentasa cost?

You can check the price of this medication from this page.

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Quantities Available:

100, 200, 300


Prolonged Release Tablet

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Pentasa (Mesalamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Pentasa (Mesalamine).