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What is Xarelto (Rivaroxaban)?

Xarelto (generic name rivaroxaban) is an oral film-coated tablet prescribed to decrease the risk of stroke or systemic embolism in nonvalvular atrial fibrillation patients.

Xarelto (rivaroxaban) is also prescribed to decrease the occurrence of and serve as prophylaxis for deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients undergoing knee or hip replacement surgery.

Xarelto drug class is an anticoagulant or a factor Xa inhibitor. Xarelto medication is known to have no direct action on platelet aggregation, yet can indirectly impede the formation of clots by preventing the conversion of prothrombin to thrombin.

This is a brand-name medication. It is also available in Xarelto generic form.

How to Use Xarelto (Rivaroxaban)

You must read the medication information guide prior to taking this product. Be familiar with Xarelto uses and what to expect after administering. It is important to use this medication precisely as prescribed.

This medication is normally administered once daily with evening meal or twice daily depending on the purpose and the medical condition being treated. Do not change your Xarelto dosage and avoid taking it more frequently than prescribed. The 2.5 mg and 10 mg tablets may be taken on a full or empty stomach. The 10 mg and 20 mg tablets should be taken with food. It is important to take this medication at the same time every day.

Swallow the Xarelto tablet whole with a glass of water. It is preferable not to cut or crush the tablet. If a patient is unable to swallow the tablet whole, then the 10 mg, 15 mg, and 20 mg tablets may be crushed and mixed with a small amount of applesauce followed by regular food. This mixture should be consumed immediately.

It takes about 2-4 hours for this anticoagulant to take full effect and the medication stays in the body for approximately 24 hours.

Side Effects of Xarelto (Rivaroxaban)

Common Xarelto side effects include the following:

  • Easy bruising
  • Minor bleeding
  • Nausea

Some people taking this medication have also reported of tiredness. This prescription is not supposed to cause weight changes.

Most of the adverse effects of this oral medication are mild. If any reactions worsen, it is best to see your doctor.

Serious Side Effects

Any serious side effect listed below should be reported to your healthcare provider if it occurs:

  • Persistent or frequent nosebleeds
  • Bowel or bladder problems
  • Unusual weakness, numbness, or paralysis
  • Unusual pain, swelling, or discomfort
  • Prolonged bleeding from cuts
  • Vomiting with blood
  • Persistent dizziness
  • Fainting
  • Blood in the stool
  • Difficulty swallowing
  • Confusion
  • Vision changes
  • Weakness on one side of the body
  • Trouble speaking

Allergic Reactions

Tell your doctor if you previously had an allergic reaction to rivaroxaban or any of the inactive components of this product. Seek emergency attention once you observe the following:

  • Itching
  • Rashes
  • Hives
  • Severe dizziness
  • Swelling of the face and throat
  • Wheezing
  • Trouble breathing

Xarelto (Rivaroxaban) Precautions

Taking this oral anticoagulant may be contraindicated for people who have any history of:

  • An allergy to rivaroxaban
  • Recent major injuries or surgeries
  • Bleeding problems
  • Blood disorders
  • Stroke
  • Liver disease
  • Kidney disease
  • Certain types of cancer
  • Antiphospholipid syndrome
  • Hereditary enzyme problems
  • Retinopathy

Patients who are prescribed with this oral tablet must also be informed of the possible drug interactions. There are many major, moderate, and minor drug interactions with Xarelto. Be sure to discuss any medications you are currently taking with your prescriber before taking Xarelto. Xarelto may have a major interaction with the following:

  • Antifungals (ketoconazole, fluconazole, itraconazole)
  • Antiseizure medications
  • HIV medications
  • Mifepristone
  • Clopidogrel
  • Blood thinners, like warfarin
  • Aspirin
  • Certain pain medications (diclofenac, meloxicam, ketoprofen)
  • Certain antidepressants

While on this prescription medication, grapefruit or grapefruit juices must be avoided as they can increase the level of the medication in the system. Unlike warfarin, the Xarelto medication is not affected by caffeine-containing beverages.

It is best to avoid anything with alcohol while taking this oral medication as alcohol can elevate the risk of major bleeding episodes.

This type of medication must be avoided during pregnancy.

It is unknown if the contents of this medication can be excreted through breast milk. Discuss the possible effects, especially on breastfed infants, with your doctor if you are pregnant or planning on becoming pregnant.

Xarelto Form and Strength

This prescription can be availed in the following forms and strengths:

  • Xarelto, film-coated tablets
    • 2.5 mg
    • 10 mg
    • 15 mg
    • 20 mg
  • Rivaroxaban, tablets
    • 15 mg
    • 20 mg

FAQ

Is Xarelto a blood thinner?

This prescription is a blood thinner. When taking this medication, patients must be aware that this can increase the risk of serious bleeding.

Is Xarelto an anticoagulant?

Yes, this medication is classified as direct oral anticoagulant or DOAC. It prevents blood clots from forming.

Is there a cheaper alternative to Xarelto?

There are some cheaper alternatives to Xarelto in the market. One of these is warfarin. However, these products work differently from one another.

What is generic Xarelto?

The generic form of Xarelto is rivaroxaban. Both the generic and brand versions need a prescription in order to purchase.

 

References:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022406s015lbl.pdf

https://www.xarelto-us.com/

https://www.webmd.com/drugs/2/drug-156265-1153/xarelto-oral/rivaroxaban-oral/details

https://www.drugs.com/xarelto.html

https://www.rxlist.com/xarelto-drug.htm

Brand Name:

Xarelto

Scientific Name:

Rivaroxaban

Other Names:

Rivaroxaban, Xarelto

Strength(s):

2.5mg, 10mg, 15mg, 20mg

Quantities Available:

10, 28, 30, 56, 84, 90, 100, 112, 180

Formulation:

Film Coated Tablet, Tablet

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Xarelto (Rivaroxaban). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Xarelto (Rivaroxaban).


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