Arthrotec (Diclofenac/Misoprostal) from Maple Leaf Medications.

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Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Arthrotec 50mg/200mcg 180 $203.00 Add To Cart
Arthrotec 75mg/200mcg 180 $252.00 Add To Cart
Dosage: 50mg/200mcg
Quantity: 180
Price: $203.00
Dosage: 75mg/200mcg
Quantity: 180
Price: $252.00

Arthrotec Uses

Arthrotec, with the generic name diclofenac sodium and misoprostol, is an oral medication indicated to treat signs and symptoms of osteoarthritis-OA and rheumatoid arthritis-RA among people who are at risk of having NSAID-induced gastric and duodenal ulcers. Arthrotec helps lessen pain, redness, swelling, stiffness, and decreased range of motion due to inflamed joints.

This is available in Arthrotec 75 mg per 200 mcg and 50 mg per 200 mcg tablet forms.

How does Arthrotec work?

Arthrotec combines a nonsteroidal anti-inflammatory medicine (NSAID) with a prostaglandin E1 mimic. Arthrotec works by inhibiting prostaglandin synthesis, which mediates inflammation. It also increases the production of bicarbonate and mucus. It also inhibits basal and nocturnal gastric acid secretion.

How to use Arthrot

To begin, read the medication information sheet included with this medicine. Do not use Arthrotec medication if you have not yet fully understood the drug information, warnings, and precautions printed in the guide. If you have questions about using this treatment or need further medical advice, you can ask your physician or pharmacist.

Take Arthrotec orally. You must take it with a meal to avoid stomach upset and diarrhea. Swallow the medication whole and drink a full glass (240mL) of water right after. Do not lie down for ten minutes after taking this drug. Also, do not crush, cut, or chew the tablet because doing so may increase the risk of side effects.

Remember to take this oral medication regularly and exactly as directed. A dosing schedule helps you avoid missing a dose. Do not alter your dosing and length of treatment as it depends on your medical condition, response to treatment, or other medications you are taking. Further, keep taking this drug and do not stop taking it abruptly even if you feel better.

Side effects of Arthrotec

Common side effects:

  • Nausea
  • Dizziness
  • Headache
  • Drowsiness
  • Heartburn
  • Gas
  • Bloating

Mostly, the side effects caused by Arthrotec are mild and will resolve even without intervention. If the adverse reactions persist or get worse, you should hold the drug and consult your doctor or any health care professional. In addition, you must report side effects, such as:

  • High blood pressure or hypertension
  • Severe diarrhea
  • Dehydration
  • Palpitations
  • Painful swallowing
  • Ringing in the ears
  • Easy bruising or bleeding
  • Irregular periods
  • Unexplained stiff neck
  • Seizures
  • Changes in urine output
  • Symptoms of heart failure (shortness of breath, unusual tiredness, sudden weight gain, swelling of the lower extremities)
  • Signs of liver disease (severe abdominal pain, dark urine, yellowish eyes and skin, persistent vomiting)

This is not a full or complete list of Arthrotec’s side effects.


Before using this oral medication, you must disclose your complete medical history with your physician, especially stroke, blood disorders, clotting problems, gastrointestinal problems, liver disease, heart disease, hypertension, aspirin-sensitive asthma, and swelling. Certain diseases and disorders may affect how your body will respond to this drug. Furthermore, you must talk about all the prescription drugs and nonprescription drugs you are using because of possible drug interactions.

Continually watch out for an allergic reaction while on this treatment. Do not take this oral drug if you have a known allergy to diclofenac, misoprostol, other aspirin or NSAIDs, and any inactive ingredients each tablet may contain. Call your local emergency line once you notice signs of hypersensitivity, such as hives, swelling of the face, severe dizziness, skin rashes, and breathing trouble.

This type of medication may cause kidney problems. This condition could further be triggered by dehydration and heart failure. To avoid dehydration, avoid using diuretics and drink enough of fluids.

Do not smoke and drink alcoholic beverages while taking this drug. Some substances from alcohol and tobacco could interact with Arthrotec and cause stomach bleeding. Alcohol could also worsen side effects, such as dizziness and drowsiness. When performing tasks that need awareness, such as driving or operating machinery, use great caution.

You could be more sensitive to the sun while on this treatment. Limit your sun exposure and avoid indoor tanning. You must also apply sunblock cream and wear protective clothing when going outdoors.

This drug could cause harm to pregnant moms and unborn babies. With this, you must not use this drug during pregnancy. On the other hand, it is unlikely to cause harm, breastfeeding moms and breastfed children.

Frequently Asked Questions

Is this medication safe?

Yes, this oral medication is proven safe and effective.

How often should I take this medication?

Your doctor may prescribe this drug twice or thrice daily.

How long will it take for this medication to work?

You may notice improvements in your signs and symptoms within two weeks of taking this drug.

Does this medication make you sleepy?

Drowsiness is among the adverse effects of this drug.

How much is the Arthrotec price?

You can check the prices of this medication from this page.

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50mg/200mcg, 75mg/200mcg

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Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Arthrotec (Diclofenac/Misoprostal). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Arthrotec (Diclofenac/Misoprostal).