Elmiron (Pentosan Polysulfate) from Maple Leaf Medications.

Elmiron (pentosan polysulfate sodium) Indications

Elmiron, generic name pentosan polysulfate sodium, is an oral prescription medication used for the treatment of bladder pain or discomfort caused by interstitial cystitis. This is prescribed for adults and children who are 16 years of age and older.

Elmiron is classified as a urinary analgesic and has low molecular weight heparin-like compound. While the exact mechanism of this medication is unknown, it is known to have an anticoagulant and a fibrinolytic effect. It forms a wall layer that will protect the bladder from irritants in the urine.

Elmiron (pentosan polysulfate sodium) Uses and Dosage

You should read the prescription leaflet before using Elmiron product.

Make sure to take Elmiron medication exactly as prescribed. This is typically taken three times daily at least one hour before or two hours after a meal. Take it at the same time every day.

Elmiron is taken by mouth by swallowing the capsule whole with a glass of water. Do not break, divide, chew, or crush this medication.

Elmiron (pentosan polysulfate sodium) Side Effects

The common side effects of Elmiron include the following:

• Headache
• Dizziness
• Nausea
• Abdominal pain
• Diarrhea
• Rash
• Bruising
• Hair loss
• Abnormal liver function tests

These side effects do not usually require medical attention. However, if they get worse, then please consult your healthcare provider.

Serious Side Effects

The severe side effects of Elmiron that need to be reported immediately are as follows:

• Bleeding gums, rectum, nose
• Blood in urine or stools
• Easy bruising
• Eye pain
• Vision changes
• Unusual tiredness
• Pain when swallowing
• Fast and pounding heartbeat
• Shortness of breath
• Heartburn
• Changes in mental state or behavior

Allergic Reactions

Do not take Elmiron if you have any allergy to pentosan polysulfate sodium, heparin, or any heparin-like medications. Seek emergency medical attention if an allergy develops while using this medication. Signs of an allergy include:

• Itching
• Hives
• Rashes
• Swollen lymph nodes
• Swelling of the face and neck
• Severe dizziness
• Wheezing
• Breathing difficulty

Elmiron (pentosan polysulfate sodium) Cautions

Elmiron may be contraindicated in people with a history of:

• Bleeding disorders (such as thrombocytopenia and hemophilia)
• Blood vessel disorders
• Liver disease
• Spleen disorders
• Gastrointestinal disorders
• Eye disorders

Know all the risks and benefits before using Elmiron during pregnancy. It is unknown if it can affect unborn babies.

It is also undetermined if Elmiron can pass through breast milk. Talk to your physician regarding the possible undesirable effects when breastfeeding.

Elmiron (pentosan polysulfate sodium) Forms and Strengths

Elmiron oral medication is available in the following forms and strengths:

• Elmiron, capsule
  • 100 mg
• Pentosan polysulfate sodium, capsule
  • 100 mg

FAQ

How long can you stay on Elmiron?

Elmiron is typically used for a minimum of six months. You must use this medication until the prescribing physician discontinues it.

How quickly does Elmiron work?

The effects of Elmiron are expected to be gradual. It usually takes three to four weeks before symptoms are relieved. For some, it may take three months.

Does Elmiron make your hair fall out?

Hair loss or alopecia is the most common adverse effect of Elmiron; however, hair is expected to grow back once the medication is discontinued.

What are the long-term side effects of Elmiron?

Taking Elmiron for a long time could put the patient at greater risk of progressive eye diseases, such as blurred vision, loss of nighttime vision, and blindness.

Resources

https://www.orthoelmiron.com/

https://www.webmd.com/drugs/2/drug-14085/elmiron-oral/details

https://www.rxlist.com/elmiron-side-effects-drug-center.htm

https://www.drugs.com/mtm/elmiron.html

https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020193s014lbl.pdf