Requip XL (Ropinirole Hydrochloride) from Maple Leaf Medications.

Requip XL (ropinirole hydrochloride) Indications

Requip XL, generic name of ropinirole hydrochloride, is prescribed to treat the symptoms of Parkinson’s disease. This medication helps improve motor function and reduce the tremors, stiffness, and slowness of movement associated with the condition.

Ropinirole works by acting as a dopamine agonist, stimulating dopamine receptors in the brain, which helps compensate for the loss of dopamine-producing cells in Parkinson’s disease. By compensating for the reduced dopamine levels, the motor function of individuals with Parkinson’s disease can be improved.

Note that Requip XL should be used under the guidance and prescription of a qualified healthcare professional.

Requip XL (ropinirole hydrochloride) Uses and Dosage

Read the patient information as it provides detailed information about the medication and its indications. In addition, this information will help you understand what to expect during treatment with ropinirole.

The starting dose of ropinirole is 2 mg once daily, the prescriber may start with a lower dose in some cases. The strength is gradually increased based on the individual’s response and tolerance to the medication—this includes increasing the dose by 2 mg per day at weekly intervals.

The maintenance dose for most patients with Parkinson’s disease ranges from 4-8 mg daily taken as a single dose with or without food. The prescriber may increase the dose up to 24 mg per day (maximum), yet doses greater than 24 mg daily are not recommended.

Ropinirole tablets should be swallowed whole with water and should not be crushed, chewed, or split. The extended-release mechanism may be compromised if the tablets are not swallowed whole. The specific timing of the dose may vary depending on the individual’s overall condition.

Take ropinirole for as long as it is prescribed. Abruptly discontinuing the medication can lead to withdrawal symptoms or a worsening of the underlying condition.

Requip XL (ropinirole hydrochloride) Side Effects

Some common side effects associated with ropinirole:

• Nausea
• Vomiting
• Dizziness
• Headache
• Drowsiness
• Abdominal pain or discomfort
• Low blood pressure

Ropinirole is generally well-tolerated, yet there are some severe side effects that can occur in rare cases. If you experience any of these severe side effects, seek urgent medical attention:

• Sudden drop or rise in blood pressure
• Severe dizziness
• Fainting
• Worsening uncontrolled movements
• Unusual strong urges
• Excessive sleepiness
• Hallucinations or psychotic-like behaviour

Allergic reactions to ropinirole may occur and can be severe. Signs may include difficulty breathing, hives, swelling of the face or throat, generalized rash, and severe itching. If these signs and symptoms manifest, seek emergency medical intervention promptly.

Requip XL (ropinirole hydrochloride) Cautions

Individuals with the following conditions should avoid using ropinirole:

• Severe liver disease
• Cardiovascular issues
• High or low blood pressure
• Kidney problems
• Sleep disorders
• Impulse control disorders
• Hallucinations or psychotic disorders

Ropinirole can interact with other medications, which may include the following:

• Other dopamine agonists
• Certain antipsychotic medications
• Antidepressants
• Antinausea medications
• Ciprofloxacin
• Opioids
• Blood pressure medications
• Estrogen-containing medications

The combination of ropinirole and alcohol is not recommended as the central nervous system depressant effects can slow brain activity and impair motor skills and cognitive function.

Ropinirole can cause drowsiness, dizziness, and impaired alertness. This effect may be more pronounced at the beginning of treatment or when the dosage is increased. Avoid driving, operating any heavy machinery, or engaging in activities that require mental alertness until you fully know how this medication affects you.

Requip XL (ropinirole hydrochloride) Form and Strength

Requip XL is available in the following strengths:

• Requip XL tablet
  • 2 mg
  • 4 mg
  • 8 mg
  • 12 mg

FAQ

Does Requip XL make you sleep?

Requip XL is a medication that can cause drowsiness and somnolence as a side effect.

Can I take Requip XL only as needed?

No, Requip XL should not be taken on an as-needed basis. This medication requires regular dosing and consistent use.

Resources

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022008s001lbl.pdf
2. https://www.webmd.com/drugs/2/drug-150670/requip-xl-oral/details
3. https://www.rxlist.com/requip-xl-drug.htm
4. https://www.drugs.com/mtm/requip-xl.html