Norvasc (Amlodipine) from Maple Leaf Medications.

Norvasc (amlodipine) Indications

Norvasc, generic name amlodipine, is an oral prescription medication used for the management of high blood pressure (hypertension) and coronary artery disease, including chronic stable angina and vasospastic angina.

Amlodipine can be used by itself or in combination with other drugs to manage hypertension and prevent chest pain related to angina. This medication is effective in managing the symptoms and minimizing the risk of complications with these conditions.

Amlodipine belongs to a class of medications known as calcium channel blockers. Calcium channel blockers relax the blood vessels and improve blood flow, which reduces the workload on the heart.

Norvasc (amlodipine) Uses and Dosage

Amlodipine is taken by mouth once daily swallowed whole with water, either with or without a meal, as per the directions of your healthcare provider. The specific dose and duration of treatment may differ based on the patient’s medical condition and response to the drug.

Avoid crushing, chewing, or breaking the tablet. If a dose is missed, take it promptly, unless the next dose is scheduled to be taken within a couple of hours. In that case, the missed dose should be skipped, and the regular dosing schedule should be continued.

Follow the prescribed dosage and other guidelines provided by your healthcare provider. Even if you feel well, avoid discontinuing the medication without consulting the prescriber, as doing so may raise blood pressure and increase the likelihood of a heart attack or stroke.

Norvasc (amlodipine) Side Effects

Mild and common side effects of amlodipine include:

• Dizziness or lightheadedness
• Drowsiness
• Tiredness
• Flushing
• Nausea
• Stomach discomfort
• Swelling of the ankles and feet

Amlodipine is typically well-tolerated. However, serious side effects, while uncommon, demand urgent medical attention. Serious side effects of amlodipine may include:

• Rapid or irregular heartbeat
• Fainting
• Chest pain and shortness of breath
• Unusual bleeding or bruising
• Yellowing of the skin or eyes

In addition, taking amlodipine may cause allergic reactions in some individuals. Signs of an allergic reaction include hives, skin rash, chest tightness, trouble breathing, and swelling of the face. Emergency medical help should be sought if these symptoms occur as severe allergies can be life-threatening.

Norvasc (amlodipine) Cautions

Individuals with the following conditions should not use amlodipine:

• Severe hypotension
• Cardiogenic shock
• Aortic stenosis
• Hepatic impairment

Amlodipine is known to interact with the following medications:

• Other antihypertensive drugs
• Beta-blockers
• CYP3A4 inhibitors
• Cyclosporine
• Simvastatin
• Digoxin

Avoid grapefruit or grapefruit juice as it contains compounds that can inhibit the enzymes responsible for breaking down amlodipine in the body. As a result, the medication may stay in the bloodstream longer and reach higher levels than intended.

Amlodipine is not recommended for use in children less than six years of age. The safety and effectiveness of this calcium channel blocker have not been established in this age group.

Norvasc (amlodipine) Form and Strength

Norvasc is available in the following forms and strengths:

• Norvasc tablet
  • 5 mg
  • 5 mg
  • 10 mg
• Amlodipine tablet
  • 5 mg
  • 5 mg
  • 10 mg

FAQ

How quickly does Norvasc lower BP?

Norvasc (amlodipine) may start to work within a few hours after administration, and its maximum effect is usually reached within one to two weeks of starting treatment.

Does Norvasc affect sleep?

Norvasc (amlodipine) is not known to affect sleep directly. However, in rare cases, this medication may cause insomnia as a side effect.

Resources

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf
2. https://www.drugs.com/norvasc.html
3. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abd6a2ca-40c2-485c-bc53-db1c652505ed
4. https://www.webmd.com/drugs/2/drug-5942/norvasc-oral/details