Nocdurna (Desmopressin) from Maple Leaf Medications.

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Formulation : Orally Disintegrating Tablet
Drug Name Dosage Quantity Price Buy Now
Nocdurna 25mcg 90 $160.00 Add To Cart
Nocdurna 50mcg 90 $160.00 Add To Cart
Dosage: 25mcg
Quantity: 90
Price: $160.00
Dosage: 50mcg
Quantity: 90
Price: $160.00

Nocdurna Uses 

This oral medication is indicated to treat nocturia caused by excessive urination at night in adults who awaken at least two times per night to urinate. It contains desmopressin, which belongs to a class of drugs known as antidiuretics (also known as vasopressin analogs).

How does Nocdurna work? 

Nocturia is when you wake up from the intended sleep time because of the desire to void. Typically, this is due to low levels of vasopressin at night, among other factors.

When this medication is taken correctly and absorbed into the bloodstream, it mimics the effects of naturally produced vasopressin in the body. It helps regulate vasopressin levels by making the kidneys store water instead of getting rid of it in the urine. As a result, this action leads to less urine production at night.

Nocdurna Dosage 

The dosage and frequency of the Nocdurna tablet differ from person to person. It will depend on the severity of the patient’s condition, gender, and tolerance to the medication. This drug is available in disintegrating tablets with two strengths: 25 mcg and 50 mcg.

The recommended daily dose for male patients in treating nocturia is 50 mcg. Meanwhile, for women, the suggested dosage is 25 mcg.

Do not increase or alter your dose without consulting your doctor, as this may make you more prone to unwanted side effects of this medication.

Directions on how to take Nocdurna 

Make sure to read all medication guidelines related to Nocdurna. If you are unsure how to administer this pill, consult your doctor and seek clarification.

This medication is an orally disintegrating tablet that needs to be placed under the tongue one hour before bedtime without drinking liquids because it quickly dissolves on its own.

When taking this drug, limit your water or fluid intake before and after taking this medication. Also, avoid drinking alcohol or coffee in the evening since this can make you more likely to urinate frequently.

Nocdurna Side Effects 

The following are the common side effects of antidiuretic pills that may resolve with time without medical intervention when your body has adjusted to the medication: 

  • Headache 
  • Nausea 
  • Stomach upset 
  • Flushing
  • Dry mouth
  • Dizziness
  • Diarrhea
  • Fatigue
  • Cough 

If any of these side effects are becoming bothersome or if you experience the following adverse drug reactions, contact your doctor immediately: 

  • Low levels of sodium 
  • High blood pressure 
  • Rapid weight gain 
  • Severe headache
  • Seizure
  • Breathing problems
  • Fainting
  • Mood changes
  • Visual disturbances
  • Swelling (lower and upper extremities) 

Remember that this is not the complete list of the potential health concerns linked with this antidiuretic medication. 

Precautions when taking Nocdurna 

Before administering this orally disintegrating pill, tell your doctor about your medical history, especially if you have hypertension, cystic fibrosis, increased intracranial pressure, or urinary retention. Also, notify them if you are currently vomiting, having diarrhea, or have heart or kidney problems, as this will let them decide if this drug is safe for you. 

Avoid taking Nocdurna if you have moderate or severe kidney disease, SIADH, or low serum sodium levels to prevent exacerbating your medical condition. 

Do not take this drug if you are allergic to the ingredients of this medication. Seek medical attention when you experience the following allergic reactions: rashes, hives, swelling of the face and lips, throat tightness, or trouble breathing.

Inform your doctor about the medication you are taking, especially if you are taking water pills and steroids, as this can make you more prone to hyponatremia.

Keep and store this medication accordingly, away from the reach of the children.

How much does Nocdurna cost in Canada? 

Because the cost of drugs in Canada is regulated by its government, Nocdurna is generally more affordable than in other countries. The price of this tablet varies depending on the quantity you buy. You can check our pricing information at the top of this page.

At Maple Leaf Meds, we make sure to provide clients with excellent and trustworthy products at a reasonable cost.

FAQS about Nocdurna 

Is Nocdurna safe for the elderly? 

Make sure to be cautious when administering this drug to older adults because kidney function deteriorates as you age. Since kidneys are responsible for the excretion of this drug, they are more prone to developing electrolyte imbalance and low serum sodium, which can be detrimental.

Is it recommended to drink fluids when taking Nocdurna? 

No. When taking this pill, limit your fluid intake as prescribed by your doctor because this can cause water accumulation leading to hyponatremia, which can cause serious health implications, such as convulsions.  

It is best to avoid drinking fluids for one hour before and eight hours after taking this pill.

Can I take Nocdurna during pregnancy? 

There is no adequate information that taking this medication can cause harm to your baby. If you are pregnant and have nocturia, discuss with your doctor if this drug is safe for you and your baby. 


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25mcg, 50mcg

Quantities Available:



Orally Disintegrating Tablet

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Nocdurna (Desmopressin). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Nocdurna (Desmopressin).

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