Imuran (Azathioprine) from Maple Leaf Medications.
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Imuran, with the generic name azathioprine, is an oral medication indicated to prevent rejection in renal homotransplantation (kidney transplant). This is usually given along with other medication to support the new kidney is functioning normally. This is also prescribed for the management of active rheumatoid arthritis (RA). It reduces signs and symptoms, such as pain in the joint/s, swelling, stiffness, weight loss, and fatigue.
This is available in Imuran 50 mg tablet.
Imuran Mechanism of Action
This immunomodulator works as an antagonist of purine metabolism, which results in the inhibition of DNA, RNA, and protein synthesis. DNA, RNA, and protein synthesis are essential in the synthesis of B cells and T cells. This weakens the immune system allowing the body to accept a new kidney and preventing the body from further damaging the joints.
How to use Imuran
Read the medicine information sheet that comes with the product first. Do not take any immunosuppressant without fully understanding the drug information and adverse reactions printed in the manual. If you have queries regarding the effects of this prescription drug or need additional medical advice, you should ask your doctor or pharmacist.
Take the tablet orally. This is usually prescribed once or twice daily or as prescribed by your physician. To avoid stomach upset, take this drug with a meal. Swallow the tablet whole and drink water right after. Do not split or crush the tablets. Doing so can produce powder or dust that, if inhaled, may cause side effects to you or people around you.
Be sure to take this drug exactly as directed. To avoid skipping medications, make a dosage regimen. Do not alter your dosage and length of treatment as it will be based on your weight, medical condition, and response to therapy. Also, do not stop taking this medication abruptly or even for a short time to avoid worsening conditions.
Imuran Side Effects
Common side effects:
-Nausea and vomiting
-Loss of appetite
For the most part, the side effects brought about by this medication are mild and should be resolved on their own. If the adverse reactions do not get better or get worse, you should hold the tablets and consult your doctor or any healthcare professional. You must also report serious adverse effects, such as:
-Worsening joint and muscle pain
-Symptoms of liver disease (severe abdominal pain, persistent vomiting, dark urine, yellowish eyes, and skin)
-Symptoms of progressive multifocal leukoencephalopathy or PML (weakness, clumsiness, loss of coordination or balance, difficulty talking, seizure, vision changes, sudden change in thinking)
This is not a full or complete list of the side effects of Imuran.
Precautions when using Imuran
Before you begin taking Imuran medication, you should disclose your entire medical history to your physician. This should include any history of cancer, enzyme disorders, liver disease, and kidney disease. Certain disorders or diseases may significantly impact how your system will respond to the treatment. Further, you should talk about all prescription drugs, nonprescription drugs, herbal products, or supplements you are taking because of possible drug interactions with this immunosuppressive agent.
Always be cautious of an allergic reaction while on this medication. Avoid taking this prescription drug if you have a known allergy to azathioprine, mercaptopurine, or any inactive ingredients each tablet may contain. Immediately discontinue medication and alert your local medical emergency line once you experience signs of hypersensitivity, such as breathing difficulty, severe dizziness, skin rashes, swelling of the face and neck, and hives/itchiness.
Since this medication is an immunosuppressant, you are more likely to get infected, or your current infection may worsen while taking this drug. Practice good personal hygiene at all times. You should also avoid contact with patients who have an infection like flu, chickenpox, or measles. Do not get vaccinated or immunized, and avoid people who recently received live vaccines.
This medication has the potential to raise the risk of skin cancer. To avoid this condition, limit your time under the sun and avoid indoor tanning. Apply sunscreen and wear protective clothing when going outside.
Pregnant and breastfeeding moms must not take this medication. This prescription drug is known to cause harm to an unborn baby. Reliable birth control methods may be necessary while on this medication. Further, this can also pass into the breastmilk and cause undesirable effects on a nursing baby.
Frequently Asked Questions
-Is Imuran a DMARD?
This medication is an immunosuppressant and a disease-modifying anti-rheumatic drug (DMARD).
-Can I use Imuran for Crohn’s disease?
Some physicians also use this drug for Crohn’s disease and ulcerative colitis.
–How long will it take for Imuran to work?
If you are taking this drug for RA, it may take two months before you notice improvements in your condition.
–Does Imuran cause weight gain?
Weight gain is not directly linked to this medication.
–How much does Imuran cost?
You may check the prices of this prescription medication from this page.
Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Imuran (Azathioprine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Imuran (Azathioprine).