Climara Pro Patch (Estradiol/Levonorgestrel) from Maple Leaf Medications.

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Formulation : Patch
Drug Name Dosage Quantity Price Buy Now
Climara Pro Patch 45/15mcg 4 $280.00 Add To Cart
Climara Pro Patch 45/15mcg 12 $820.00 Add To Cart
Climara Pro Patch
Dosage: 45/15mcg
Quantity: 4
Price: $280.00
Climara Pro Patch
Dosage: 45/15mcg
Quantity: 12
Price: $820.00

Climara Pro Patch is a female hormone therapy patch that’s used to resupply the body with estrogen to improve post-menopausal symptoms. It contains two female hormones: estrogen (from the active ingredient estradiol) and progestin (from the active ingredient levonorgestrel). After menopause occurs, the female endocrine system is unable to produce a sufficient amount of estrogen due to changes in the body.

The active ingredients in Climara Pro Patch are administered by applying the patch to the skin, where the medical ingredients can be absorbed into the skin. There are many other options for post-menopausal treatment that have different routes of administration, such as oral tablets or vaginal inserts. Such options are sometimes considered first-line options. You should talk to your doctor to find out which one works best for you before using Climara Pro Patch.

Combination Therapy

The combination of estradiol and levonorgestrel helps combat symptoms occurring after menopause and reduces the risk of other conditions developing as a result of the changes to the body’s hormones. Estradiol helps maintain healthy levels of estrogen in the body to reduce symptoms caused by hormone fluctuations, while levonorgestrel supplies the body with the progestin it needs, reducing the risk of uterine cancer.

Who should not use this medication?


Tell your doctor if you have any hypersensitivities prior to using Climara Pro Patch and seek medical help if you have an allergic reaction. Signs of an allergic reaction include: swelling of the face or throat, red skin, rashes, trouble breathing.


Do not smoke while using this patch. Nicotine increases the risk of adverse events including strokes and blood clots.


If you have recently had surgery, or if you are about to go into surgery, then it may not be the best time to use Climara Pro Patch. Prolonged laying or sitting can increase the risk of blood clotting. Tell your doctor about any surgeries planned so that they can ensure the safe use of this patch.

If you are receiving an MRI scan, you must tell the staff that you are using Climara Pro Patch as it can interfere with the result.

Other Medical Conditions:

Always tell your doctor about your medical history before using any prescribed medication. You may need to take extra precautions if you have a history of vaginal bleeding, blood clots, heart disease, stroke, liver or kidney disease, breast cancer, diabetes, high blood pressure, blood disorders, obesity, lupus, and mood disorders.

Climara pro patch side effects

Common side effects:

  • Skin rash, redness, or irritation where Climara Pro Patch was applied
  • Abdominal pain
  • Nausea
  • Vomiting
  • Bloating
  • Headache
  • Breast soreness or tenderness
  • Weight fluctuations

Rare side effects (talk to your doctor if you experience any of these):

  • Swelling in extremities
  • Increased thirst
  • Frequent urination
  • Persistent nausea
  • Severe stomach pain
  • Vaginal discharge
  • Irritation in or around the vagina
  • Unusual vaginal bleeding
  • Breast lumps
  • Memory loss
  • Depression
  • Anxiety

Very rare side effects (Get IMMEDIATE medical help):

  • Blood clotting
  • Heart attack
  • Stroke
  • Muscle or joint pain
  • Sweating excessively
  • Severe headache
  • Weakness or numbness on one side of the body
  • Confusion
  • Slurred speech
  • Vision changes
  • Swelling in extremities
  • Numbness in extremities
  • Trouble breathing
  • Coughing blood
  • Extreme dizziness

Climara pro patch withdrawal

Hormone Replacement Therapies (HRTs) such as Climara are known to cause withdrawal symptoms if stopped abruptly. The symptoms are very similar to those experienced soon after menopause, including hot flashes, fatigue, and irritability. This is because the symptoms are caused by a sudden, massive decline in the amount of estrogen in the body. Talk to your doctor or pharmacist about how to mitigate and reduce these symptoms if you need to stop using an HRT for any reason.

Climara Pro Patch Doses

Climara Pro Patch is applied to the skin once per week. For proper use, the patch should be applied to different locations each time and should be replaced on the same day every week. Do not apply more than one patch at a time.

To apply, place the adhesive side down on a relatively flat, smooth portion of skin. Avoid applying Climara Pro Patch to any areas that could chafe against it and rub it off. If your patch falls off simply use a new one for the remainder of the weekly duration. Ask your doctor for more detailed instructions if you are unsure.

How much does Climara Pro Patch cost in Canada? 

The price of this patch can be quite expensive but reasonable for its effectiveness.  

Check the top of this page for our prices.

Frequently Asked Questions 

Does Climara Pro cause weight gain? 

Bloating and modest weight gain may occur while using this medication. However, rapid gain in weight is not normal and not a common side effect. If you gain weight suddenly, you must report it to your physician.

What is the difference between Climara and Climara Pro? 

While both transdermal patches contain estradiol, Climara Pro also has levonorgestrel, which is a progestin. These medications are both indicated to manage menopausal symptoms, including hot flashes and vaginal dryness.

Where is the best place to put Climara Pro patch? 

You must apply Climara Pro Patch on the lower abdomen or on the buttocks. Do not put it in an area where it can easily be removed, like the waistline.

How do you wean off Climara Pro? 

Your physician may lower your dose every two to four weeks to wean you off this medication. You must not discontinue applying this patch abruptly to avoid withdrawal reactions.

Can you cut Climara Pro Patch in half? 

No, you must never cut your transdermal patch in half. Doing so may affect the effectiveness of the product, and it may also increase the side effects.

Can I buy Climara Pro online? 

Yes, you may purchase transdermal patches like Climara Pro online. Note that it is necessary to provide a valid prescription coming from your doctor when buying this product. 

Brand Name:

Climara Pro Patch

Scientific Name:


Other Names:

Climara Pro Patch



Quantities Available:

4, 12



Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Climara Pro Patch (Estradiol/Levonorgestrel). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Climara Pro Patch (Estradiol/Levonorgestrel).

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