Climara Patch (Estradiol) from Maple Leaf Medications.

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Formulation : Patch
Drug Name Dosage Quantity Price Buy Now
Climara Patch 25mcg 4 $45.00 Add To Cart
Climara Patch 25mcg 8 $76.00 Add To Cart
Climara Patch 50mcg 4 $62.50 Add To Cart
Climara Patch 50mcg 8 $110.00 Add To Cart
Climara Patch 50mcg 12 $155.00 Add To Cart
Climara Patch 75mcg 12 $115.00 Add To Cart
Climara Patch 75mcg 24 $216.00 Add To Cart
Climara Patch 100mcg 12 $90.00 Add To Cart
Climara Patch
Dosage: 25mcg
Quantity: 4
Price: $45.00
Climara Patch
Dosage: 25mcg
Quantity: 8
Price: $76.00
Climara Patch
Dosage: 50mcg
Quantity: 4
Price: $62.50
Climara Patch
Dosage: 50mcg
Quantity: 8
Price: $110.00
Climara Patch
Dosage: 50mcg
Quantity: 12
Price: $155.00
Climara Patch
Dosage: 75mcg
Quantity: 12
Price: $115.00
Climara Patch
Dosage: 75mcg
Quantity: 24
Price: $216.00
Climara Patch
Dosage: 100mcg
Quantity: 12
Price: $90.00

What is Climara?

Climara, with the generic name estradiol, is a transdermal patch indicated to treat vasomotor and vaginal symptoms due to menopause. It lessens symptoms such as hot flashes and vaginal dryness. It also treats hypoestrogenism related to hypogonadism, castration, and primary ovarian failure. This drug can also help to prevent postmenopausal osteoporosis.

This endogenous estrogen in a transdermal system work by binding to subtypes of estrogen receptors. This is considered more potent than estrone and estriol at the estrogen receptor. This is available in Climara Patch 0.025 mg/day, 0.05 mg/day, 0.075 mg /day, and 0.1 mg/day.

How to use Climara Patch

You should begin by reading the information leaflet that comes with the medication. Do not use this patch unless you fully understand the drug information and instructions printed in the guide. In case you need further medical advice or have questions on how to use this transdermal patch, you may ask your doctor or pharmacist.

Remember to use Climara Patch regularly and as directed by your doctor for best results. Make a dosing schedule so as not to forget when to replace the patch. Typically, each patch is worn for one week. However, your dosage will depend on your medical condition and response to treatment.

Step by step guide in using Climara Patch:

  1. Open the Climara pouch by tearing at the notch. Do not use scissors.
  2. A strong plastic adhesive is applied to this oval-shaped transparent patch, which is covered by a clear plastic film. To apply the patch, first, remove the clear plastic film attached to the thick plastic adhesive.
  3. Apply your patch to a clean and dry area in your lower abdomen or buttocks, NEVER IN YOUR BREAST. Never touch the sticky part of the patch with your fingers. Note: The patch must be applied on different areas each time it is needed to be replaced.
  4. Press the patch firmly against the skin and rub the patch’s edges to make sure that it will stay in place.
  5. After a 7-day period, remove Climara by detaching it slowly from the skin. If there is some remaining residue, wait for 15 minutes before you gently rub the area with an oil-based cream or lotion.
  6. To dispose the patch, fold the sticky side together and throw it properly.

Climara Side Effects

Common side effects:

  • Skin irritation on the application site
  • Nausea
  • Headache
  • Abdominal discomfort
  • Bloating
  • Breast tenderness
  • Acne
  • Skin discoloration
  • Increased facial hair
  • Weight changes

Mostly, the side effects brought about by this endogenous estrogen are mild. If these adverse reactions persist or worsen, you will have to call your doctor or any healthcare provider. You also need to report severe side effects, such as:

  • Unusual vaginal bleeding
  • Breast lumps
  • Increased vaginal irritation
  • Severe abdominal pain
  • Persistent vomiting
  • Signs of blood clots (chest pain, severe headache, weakness on one side of the body, slurred speech, confusion)

This is not a full or complete list of Climara Patch side effects.


Before starting to use this patch, you must disclose your entire medical history with your physician, especially any history of heart attack, stroke, blood clots or blood clotting disorders, heart disease, liver disease, kidney disease, hypertension, diabetes, high cholesterol levels, lupus, obesity, uterus problems, gallbladder disease, asthma, seizure, migraine, certain cancers, and mental or mood changes. Some medical conditions could affect how you will respond to treatment. You also have to tell your doctor about all the prescription drugs and nonprescription drugs you are taking, as they may have drug interactions with estradiol.

Consistently lookout for an allergic reaction while using this patch. Do not use this transdermal patch if you have a known allergy to estradiol or any inactive ingredients this drug may contain. Signs of hypersensitivity are breathing trouble, severe dizziness, hives, swelling of the face, and skin rash. Seek emergency medical assistance if this occurs.

This estradiol patch may cause blood clots. To prevent this, avoid smoking or using tobacco, especially for women above the age of 35. Also, inform your physician if you will be confined in a certain position for a long time, such as in a long-haul flight or surgery. Limited movements could also increase the risk of stroke and blood clots.

If you are undergoing an MRI test, tell any healthcare professional present that you have a patch on. Climara may contain metal and cause a serious burn. You may have to remove the patch before the procedure and apply a new one afterward.

You are more prone to melasma while on Climara Patch. Melasma is the dark, blotchy area on the skin. Limit your time outdoors because sun exposure could worsen this condition. In addition, avoid indoor tanning and wear sunblock cream when going out.

Pregnant and breastfeeding moms should avoid Climara Patch because of the harmful effects that it could cause to unborn babies and breastfed children. Always remember that potential benefits must be greater than the potential risks.

Frequently Asked Questions

Is Climara Patch bioidentical hormone?

Yes, this product contains bioidentical hormones.

What should I do if the patch falls?

If the patch falls off, apply a new patch and replace it as scheduled.

Does this medication cause weight gain?

The direct link between Climara patch and weight gain is due to the changes in hormone levels.

What is the difference between Climara Pro and Combipatch?

On Climara Pro vs Combipatch, both are used to treat symptoms of menopause, but the former could also be used to manage osteoporosis.

What is the difference between Climara and Vivelle?

On Climara vs Vivelle, both are used to treat symptoms of menopause, but Vivelle could also be used to treat ovarian disorders such as infertility and abnormal vaginal bleeding.

Can I purchase this patch online?

If you have a doctor’s prescription, you can purchase this transdermal system online.

Brand Name:

Climara Patch

Scientific Name:


Other Names:

Climara Forte, Climara Patch


25mcg, 50mcg, 75mcg, 100mcg

Quantities Available:

4, 8, 12, 24



Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Climara Patch (Estradiol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Climara Patch (Estradiol).

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