Vagifem Vaginal Tablet (Estradiol) from Maple Leaf Medications.

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Formulation : Vaginal Tablets
Drug Name Dosage Quantity Price Buy Now
Vagifem Vaginal Tablet 10mcg 18 $58.00 Add To Cart
Vagifem Vaginal Tablet 10mcg 36 $93.00 Add To Cart
Vagifem Vaginal Tablet 25mcg 30 $46.75 Add To Cart
Vagifem Vaginal Tablet
Dosage: 10mcg
Quantity: 18
Price: $58.00
Vagifem Vaginal Tablet
Dosage: 10mcg
Quantity: 36
Price: $93.00
Vagifem Vaginal Tablet
Dosage: 25mcg
Quantity: 30
Price: $46.75

What is Vagifem? 

Vagifem (generic: estradiol) Vaginal Tablet is used by women to manage vaginal symptoms of menopause, such as vaginal itching, dryness, and burning. This vaginal medication is available in Vagifem 25 mcg and 10 mcg tablets. 

This female hormone medication works by decreasing the high levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and gonadotropins on menopausal women. As a result, it could maintain the balance of secondary sexual characteristics and the equilibrium of the female reproductive system. 

How to use Vagifem Vaginal Tablet 

To initiate, read the medication information leaflet provided with this drug. Do not administer Vagifem if you have not fully and thoroughly understood the information and/or instructions in the guide. Do not hesitate to ask your doctor or physician if you have more questions or need further medical advice. 

Administer this vaginal tablet exactly as prescribed. Follow a dosing schedule for best results. This medication is usually prescribed once a day for two weeks and twice a week thereafter. However, your dosage would still depend on your medical condition and response to treatment. Never alter your dose and stop using Vagifem abruptly unless advised by a healthcare professional. 

Step by step guide in Vagifem insertion: 

  1. Always wash and dry your hands before vaginal tablet insertion to prevent infections or contamination. 
  2. Tear off to open the applicator pack. Take the applicator and hold it with your dominant hand in a way that the index finger can push the plunger. 
  3. Choose a position that is comfortable for vaginal tablet insertion. With the help of your non-dominant hand, guide and slowly insert the applicator into the vaginal opening. Half of the applicator should be inserted inside the vagina. 
  4. Once properly inserted, push the plunger fully to release the tablet into the vagina. 
  5. Gently take out the applicator and discard it properly. 

Side effects 

Common side effects of Vagifem Tablets: 

  • Nausea 
  • Dizziness 
  • Headache 
  • Bloating 
  • Stomach cramps or discomfort 
  • Breast tenderness 
  • Acne 
  • Increased facial hair 
  • Weight loss or weight gain 

Most side effects of this medication are mild and temporary. If the side effects you are experiencing persist or worsen, consult your healthcare provider. In addition, seek immediate help if you experience severe adverse effects such as: 

  • Seizures 
  • Fainting 
  • Confusion 
  • Chest pain 
  • Breathing difficulty 
  • Unusual vaginal bleeding 
  • Increased vaginal discharge 
  • Breast lumps 
  • Severe abdominal pain 
  • Persistent vomiting 
  • Mental or mood changes 
  • Dark urine 
  • Increased urination 
  • Yellowish skin 
  • Vision changes 

Note that this is not a complete and full list of this medication’s side effects. 


Before using this vaginal medication, disclose your full medical history to your physician, especially any history of stroke, heart disease, blood clots, kidney disorder, liver disease, hormonal problem, diabetes, hypertension, mental disorders, seizure, or cancer. Some medical conditions may greatly impact how your body would respond to Vagifem. Additionally, tell your doctor about all the medications and supplements you are taking as they could interact with estradiol. 

It is crucial to watch out for Vagifem allergy. Do not use this tablet if you have a known allergy to estradiol or any inactive ingredients this drug may contain. Seek emergency help and discontinue medication if you observe signs of hypersensitivity response such as difficulty breathing, skin rashes, swelling of the face, hives, and severe dizziness.  

As this medication increases the risk of blood clots, consult your doctor if you will undergo surgery, go on a long haul flight, or be in any situation that could limit or restrict your movements. It is necessary to take precautions or discontinue medication temporarily. 

Do not smoke or use tobacco while on Vagifem. The substances they contain may aggravate the or trigger hypertension, heart attack, and blood clot formation. Women 35 years and older are more prone to this condition. 

Limit exposure to the sun to minimize dark patches on the skin that could be caused by this medication. Sun exposure could worsen your skin condition. To avoid this, apply sunblock lotion and wear protective clothing when going outdoors. 

Frequently Asked Questions 

Is Vagifem Vaginal Tablet safe? 

A lot of menopausal women have been using Vagifem. This is a safe and effective way to address vaginal symptoms of menopause. 

Can Vagifem Vaginal Tablet treat hot flashes and mood changes? 

Vagifem Vaginal tablets could only manage vaginal symptoms of menopause. 

What should I do if a Vagifem tablet falls out? 

If a Vagifem tablet falls out, discard it and insert another tablet using a new applicator. 

Does Vagifem cause weight gain? 

Weight changes are among the side effects of Vagifem. 

How much does Vagifem cost? 

You may check the pricing of this product by clicking here.

If you have any questions regarding medication or basic inquiries about be sure to contact us in writing. Or, if you need to speak to a live representative, you can call our toll-free number at 1-800-998-4016, Monday to Friday, 6 am to 6 pm, and Saturdays from 7 am to 4 pm.
Maple Leaf Medications is accredited by the Canadian International Pharmacy Association (CIPA). We partner with licensed pharmacies in Canada and other countries to provide you with medication choices and affordable drug prices.

Brand Name:

Vagifem Vaginal Tablet

Scientific Name:


Other Names:

Vagifem Vaginal Tablet


10mcg, 25mcg

Quantities Available:

18, 30, 36


Vaginal Tablet, Vaginal Tablets

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Vagifem Vaginal Tablet (Estradiol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Vagifem Vaginal Tablet (Estradiol).