Megace (Megestrol Acetate) from Maple Leaf Medications.

Prescription Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Megace 160mg 30 $146.00 Add To Cart
Megace 160mg 90 $421.00 Add To Cart
Dosage: 160mg
Quantity: 30
Price: $146.00
Dosage: 160mg
Quantity: 90
Price: $421.00

( Affordable Generic Alternatives )

Buy Megestrol Acetate Megestrol Acetate

Prescription Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Megestrol Acetate 40mg 100 $149.00 Add To Cart
Megestrol Acetate 160mg 100 $600.00 Add To Cart
Megestrol Acetate
Dosage: 40mg
Quantity: 100
Price: $149.00
Megestrol Acetate
Dosage: 160mg
Quantity: 100
Price: $600.00

What is Megace Used for? 

Megace’s generic name is megestrol acetate, a synthetic female hormone similar to progesterone. It belongs to a class of drugs called progestins. It is used to treat patients with cancer of the breast or uterine lining. Also, it is used for recurrent, inoperable, or metastatic cancer.

How does Megace work? 

The primary function of megestrol is to over-power the effects of estrogen by increasing progesterone levels. Studies show that estrogen binds to estrogen receptors in cancer cells which results in the rapid proliferation of these cells. 

When megestrol acetate is taken correctly and absorbed into the bloodstream, it interferes with the stimulation of cell growth that mainly depends on estrogen. Also, it blocks the production of estrogen, which can help stop tumor growth. The decreased levels of estrogen reduce cancer cells as they can no longer grow and multiply.

Megace Dosage 

The dosage and frequency of megestrol acetate vary from one person to another. It will be determined based on the existing health problem and tolerance to therapy. This drug is available in tablet formulation with a strength of 40 mg and 160 mg. 

The recommended usual dose for patients with breast cancer is Megace 40 mg four times a day. However, the suggested dosage for patients with endometrial cancer is 40 mg to 320 mg per day, divided into several doses. 

The dosage may be titrated (increased or lowered) depending on the evaluation of your doctor and how you are responding to progestin therapy.

Directions on How to Use Megace 

Read all drug instructions prescribed by your doctor or as provided in the patient information leaflet related to megestrol. Make sure to follow all directions on how to use this progestin drug. 

As prescribed, take this drug by mouth four times a day. Remember to take megestrol at the same time each day to prevent skipping a dose. To guarantee that your body is receiving an adequate amount of this synthetic female hormone, maintain consistency in taking this drug.

Megace Side Effects 

Some people may experience the following common side effects of megestrol, which may disappear on their own: 

  • Weight gain
  • Increased appetite
  • Nausea
  • Vomiting
  • Swelling
  • Breakthrough menstrual period
  • Increased blood sugar
  • Trouble sleeping
  • Fever
  • Gas
  • Stomach upset 

If you come across any of the adverse symptoms listed below, contact your doctor and seek medical attention as soon as possible: 

  • Symptoms of blood clots: 
  • Legs (pain, swelling, warm to the touch, redness) 
  • Lungs (trouble breathing, chest pain, cough) 
  • Confusion
  • Mood changes
  • Numbness
  • Trouble speaking
  • Vision changes 

Keep in mind that this is not a comprehensive list of the potential health risks associated with megestrol.

Precautions When Using Megace 

Before starting this medicine, inform your doctor about your medical history, especially if you have an adrenal gland disorder, diabetes, or blood clots. Also, tell them if you have heart disease, kidney trouble, stomach problems, and unusual vaginal bleeding. Doing so will help your medical professional to determine if this drug is safe and appropriate for your health. 

Do not use this drug if you are allergic to megestrol or other ingredients. When administering this drug, hypersensitivity reactions may occur, such as rashes, hives, swelling of the face and lips, throat tightness, or difficulty breathing. 

Make sure to secure a negative pregnancy test before starting this medication. Also, monitor your blood sugar levels regularly, as this medication can affect it. 

Tell your doctor about the medications and supplements you are taking to avoid drug interaction with megestrol. 

Use caution when using this medication with older adults as they are more prone to the side effects of this drug, such as blood clots. 

Keep Megace out of the reach of the children and store it carefully.

How much does Megace cost? 

The price of this medication depends on the dosage and quantity you purchase. You can conveniently buy this drug from this page. 

Both generic and brand versions of this drug are available at a reasonable rate.

Frequently Asked Questions 

Is Megace safe for pregnant women? 

No. A pregnant woman should not use Megace medication.  

Before starting this therapy, you need to obtain a negative pregnancy test as this can cause harm to your unborn child. You may need to use an effective birth control method while on this medication. Consult your primary care provider for appropriate medication or other alternatives for this drug that is safe for you.

Can Megace cause weight changes? 

Yes. One of the common side effects of megestrol is weight gain. Studies show that people taking this drug have increased their appetite and caused them to gain weight.

Is Megace a chemotherapy agent? 

No. This medication belongs to a class of drugs called progestins. It is a synthetic drug with actions that are comparable to the effects of the natural female hormone (progesterone) in the body.

When is the best time to take Megace? 

Depending on the discretion of your doctor, you can take this medication with or without food. To get the most out of this medication, you must take it every day at the same time. Moreover, consistently taking it will help you remember when to take the pills. 

Brand Name:


Scientific Name:

Megestrol Acetate, Megestrol acetate

Other Names:

Magestrol, Megace, Megestrol


40mg, 160mg

Quantities Available:

30, 90, 100



Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Megace (Megestrol Acetate). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Megace (Megestrol Acetate).