Femring (Estradiol) from Maple Leaf Medications.

We don't sell this generic-version medication.

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Prescription Prescription Required
Formulation : Vaginal Ring
Drug Name Dosage Quantity Price Buy Now
Femring 0.05mg/24h 1 $740.00 Add To Cart
Femring 0.1mg/24h 1 $790.00 Add To Cart
Dosage: 0.05mg/24h
Quantity: 1
Price: $740.00
Dosage: 0.1mg/24h
Quantity: 1
Price: $790.00

What is Femring? 

Femring, with the generic name estradiol acetate, is a vaginal ring indicated to manage moderate-severe vasomotor menopausal symptoms, like night sweats & hot flashes. It can also manage moderate-severe vulvar and vaginal atrophy due to menopause. 

This is available in Femring 0.05 mg per 24 hours and 0.1 mg per 24 hours vaginal ring. 

How does Femring work? 

This soft, flexible ring with a central core that contains estradiol acetate works by increasing the downstream effects of estrogen receptor binding, which reverses some of the symptoms of menopause. It modulates the pituitary secretion of hormones like gonadotropins, follicle-stimulating hormones, and luteinizing hormones through a negative feedback mechanism. 

How to use Femring 

To begin, read the medication information sheet included with this medicine. Do not use this prescription drug if you have not yet understood the drug information or instructions in the guide provided. If you need further medical advice or have queries on correctly using this vaginal ring, you can ask your doctor or pharmacist. 

Remember to use this prescription drug exactly as prescribed. Make a schedule to know when the vaginal ring should be replaced. Do not alter your Femring dosage as it is based on your overall health condition and response to treatment. 

Step by step guide in inserting Femring: 

  1. Wash & dry your hands before the ring insertion. 
  2. Remove the vaginal ring from the packaging. 
  3. Assume a position that you are most comfortable with. 
  4. Using your thumb and index/pointer finger, press the sides of the vaginal ring together. Then, twist it into a figure-eight shape for easier insertion. 
  5. Using your other hand, hold the folds of the skin around the vagina open. 
  6. Put the tip of the ring into the opening of the vagina and use your pointer finger to push the folded ring gently into the vagina. Push it as high as you can. 
  7. If you’re done, wash your hands once again. 

To remove Femring: 

  1. Wash & dry your hands before you remove the ring. 
  2. In a comfortable position, put a finger into your vagina and hook it through the vaginal ring. 
  3. Gently pull the ring downwards until it comes out. 
  4. Using toilet paper, discard the ring correctly. 
  5. Wash your hands again after removing the vaginal ring. 

Femring Side Effects 

Common side effects: 





-stomach cramps 

-breast tenderness 

-weight changes 


Mostly, the side effects caused by this drug are mild and temporary. If the adverse reactions persist or worsen, you have to consult your doctor or any healthcare professional. Also, you should report severe side effects, including: 

-breast lumps 

-unusual vaginal bleeding 

-increased vaginal irritation or discharge 

-severe abdominal pain 

-persistent nausea and vomiting 

-yellowish eyes and skin 

-dark urine 

-increased thirst or urination 

-mental or mood changes 

-signs of blood clots (chest pain, severe headache, unusual sweating, slurred speech, weakness on one side of the body, trouble breathing, sudden dizziness) 

-toxic shock syndrome (high fever, sudden dizziness, fainting, unusual muscle pain, diarrhea, sunburn-like rash) 

This is not a full or complete list of the side effects of Femring. 

Precautions when using Femring 

Before you start taking this drug, you should disclose your complete medical history to your physician, especially blood clotting disorders, bleeding of unknown cause, certain cancers, stroke, heart problems, liver disease, kidney disease, high blood pressure, high cholesterol, and triglyceride levels, diabetes, hypothyroidism, lupus, obesity, hormone problems, mineral imbalance, asthma, seizure, gallbladder problems, porphyria, any mental or mood disorders. Some conditions may impact how your body will respond to the drug. You should also discuss all the prescription drugs, nonprescription drugs, and herbal products you are using due to possible drug interactions. 

Be watchful for an allergic reaction while using this vaginal ring. Do not use this product if you have a known allergy to estradiol, silicone, or any inactive ingredients that each ring may contain. You must seek emergency medical attention once you notice signs of hypersensitivity, such as severe dizziness, swelling of the face and neck, hives, skin rashes, and difficulty breathing. 

Avoid smoking or using tobacco while using estradiol. Tobacco has a component that could increase the risk of blood clots, stroke, heart attack, and high blood pressure, especially among women above the age of 35. 

Tell your healthcare provider if you will be confined in a certain position for an extended period. This includes going through surgery or going on a long-haul flight. This is because limited movements could also increase the risk of developing blood clots. 

This drug may cause dark and blotchy patches on the face and skin. Limit your sun exposure while using this vaginal ring and avoid indoor tanning. You should also apply sunblock cream and wear protective clothing when going out. 

Frequently Asked Questions 

Is Femring HRT bioidentical? 

Yes, this vaginal product is bioidentical. 

Can Femring (estradiol acetate) cause weight gain? 

Yes, there is a direct link between Femring and weight gain. 

What are some Femring alternatives? 

One of the alternatives for this medication is Estring. 

What is the difference between Estring and Femring? 

On Estring vs Femring, the farmer cannot address vasomotor symptoms while the latter can. 

What should I do if my medication falls off? 

If the vaginal ring falls out, rinse the ring with lukewarm water and reinsert it. </span

If you have any questions regarding medication or basic inquiries about MapleLeafMeds.com be sure to contact us in writing. Or, if you need to speak to a live representative you can call our toll free number at 1-800-998-4016, Monday to Friday, 6 am to 6 pm, and Saturdays from 7 am to 4 pm. Maple Leaf Medications Canadian Pharmacy Online.

Maple Leaf Medications is accredited by the Canadian International Pharmacy Association (CIPA). We partner with licensed pharmacies in Canada and other countries to provide you with medication choices and affordable drug prices.

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0.05mg/24h, 0.1mg/24h

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Vaginal Ring

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Femring (Estradiol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Femring (Estradiol).