Estrace (Estradiol) from Maple Leaf Medications.

Prescription Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Estrace 0.5mg 100 $39.75 Add To Cart
Estrace 1mg 84 $37.00 Add To Cart
Estrace 2mg 84 $50.00 Add To Cart
Dosage: 0.5mg
Quantity: 100
Price: $39.75
Dosage: 1mg
Quantity: 84
Price: $37.00
Dosage: 2mg
Quantity: 84
Price: $50.00

( Affordable Generic Alternatives )

Buy Estradiol Estradiol

Prescription Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Estradiol 0.5mg 90 $32.00 Add To Cart
Estradiol 1mg 100 $55.00 Add To Cart
Dosage: 0.5mg
Quantity: 90
Price: $32.00
Dosage: 1mg
Quantity: 100
Price: $55.00

What is Estrace? 

Estrace, with the generic name estradiol, is an oral medication used to manage moderate to severe vasomotor symptoms and vaginal and vulvar atrophy due to menopause. It is also used to treat several other conditions, such as breast cancer, advanced-androgen carcinoma of the prostate, and hypoestrogenism linked to castration, hypogonadism, and primary ovarian failure. It is also used to prevent osteoporosis, especially for post-menopausal women. 

This estrogen derivative is responsible for maintaining and developing the female reproductive system and secondary sexual characteristics. Estradiol is also known as the principal intracellular human estrogen and is more potent than metabolites – estrone and estriol. This hormone is known to modulate the pituitary secretion of luteinizing hormone (LH), gonadotropins, and follicle-stimulating hormone (FSH) through a negative feedback mechanism.  

This is available in Estrace dosage (generic: estradiol) 0.5 mg tablet forms. 

How to use Estrace 

To start, read the medication guide or information leaflet that comes with this product. Do not take this type of prescription drug if you have not fully understood the drug information and instructions printed in the guide. In case some information is unclear, and you have further queries about this drug, you can ask your doctor or pharmacist. 

Take this tablet orally. You may take it with or without a meal or as directed by your doctor. If you develop an upset stomach, you may have to take Estrace with food. Swallow the tablet and drink a glass of fluid right after. It is not recommended to crush, cut, or chew the tablet. 

Remember to take this prescription medication orally. Make a dosing regimen to avoid missing a dose. Do not alter your dosing or take Estrace more frequently than prescribed, as it is based on your overall medical condition & response to treatment. In addition, do not stop taking this drug abruptly without the advice of your physician. This might lead to a deterioration of the situation, 

Estrace Side Effects 

Common side effects: 





-stomach upset 

-stomach cramps 

-breast tenderness 

-weight changes 

-changes in menstrual period 

The majority of the time, the side effects generated by this medicine are minor and only last a short time. Even so, if the adverse reactions worsen or continue, you may have to hold this drug until you have consulted your doctor or any healthcare professional. Also, you should report severe side effects, including: 

-severe abdominal pain 

-breast lumps 

-persistent nausea and vomiting 

-unusual vaginal bleeding 

-mental or mood changes 

-swelling of the hands and feet 

-signs of blood clots (chest pain, severe headache, weakness on one side of the body, trouble speaking, sudden vision changes, trouble breathing, confusion) 

This is not a complete or full list of the side effects of Estrace. 

Precautions when using Estrace 

Before you start to use Estrace, you must disclose your full medical history to your physician, including any history of blood clots, certain cancers, stroke, heart disease, blood clotting disorders, unusual vaginal bleeding of unknown cause, angioedema, high blood pressure, and cardiovascular disease, diabetes, mineral imbalance, high cholesterol or triglyceride levels, uterus problems, obesity, lupus, hyperthyroidism, gallbladder disease, asthma, seizure, migraine, porphyria, any mental or mood disorders. Some conditions may impact how your body will respond to the treatment. Moreover, you should talk about all the prescription drugs, nonprescription drugs, supplements, and herbal products you are taking, because of possible drug interactions. 

Always watch out for an allergic reaction while taking this drug. Do not take this oral estrogen derivative if you have a known allergy to estradiol or any inactive ingredients it may contain. You must discontinue the medication and seek emergency medical help once you observe signs of hypersensitivity, such as skin rashes, itchiness, swelling of the face and neck, severe dizziness, and difficulty breathing. 

Avoid smoking or using tobacco while taking estradiol. Tobacco has a component that could further increase the risk of heart attack, stroke, blood clots, and high blood pressure (hypertension), especially among women 35 years of age and above. 

Talk to your healthcare provider if you will be confined in a certain position for a long time. This includes going on long-haul flights or going through surgery. This is because limited movements could also increase the risk of developing blood clots & stroke. 

This drug has the potential to develop dark and blotchy areas on the face and skin. It could be worsened by sun exposure. As much as possible, you must limit your exposure to the sun and avoid indoor tanning. Always wear sunblock cream and wear protective clothing when going outdoors. 

Frequently Asked Questions 

How often should I take Estrace? 

Your dosage and frequency will be advised by your physician, depending on your condition. 

What is the difference between Estrace and Premarin? 

On Estrace vs Premarin, the former is estradiol, while the latter is a conjugated estrogen. 

Can Estrace cause hair loss? 

In some cases, this medication could cause temporary hair loss. 

Does Estrace cause weight gain? 

Yes, this medication may cause weight gain. 

Can I buy Estrace over the counter? 

No, it is necessary to provide a valid prescription when purchasing this drug. 

Brand Name:


Scientific Name:


Other Names:

Estrace, Estradiol, Progynova


0.5mg, 1mg, 2mg

Quantities Available:

84, 90, 100



Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Estrace (Estradiol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Estrace (Estradiol).

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