Desyrel (Trazodone) from Maple Leaf Medications.

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Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Trazodone 50mg 100 $29.00 Add To Cart
Trazodone 100mg 90 $50.00 Add To Cart
Trazodone 100mg 100 $35.00 Add To Cart
Trazodone 150mg 100 $75.00 Add To Cart
Dosage: 50mg
Quantity: 100
Price: $29.00
Dosage: 100mg
Quantity: 90
Price: $50.00
Dosage: 100mg
Quantity: 100
Price: $35.00
Dosage: 150mg
Quantity: 100
Price: $75.00

What is Desyrel used for?

Desyrel (generic name: trazodone hydrochloride) is an oral medication indicated to treat major depressive disorder or MDD. This drug decreases anxiety and insomnia caused by depression. It also helps improve feelings of well-being, energy level, mood, and appetite.

This is available in Desyrel 50 mg, 100 mg, and 150 mg tablets.

How does Desyrel work?

This selective serotonin reuptake inhibitor (SSRI) has an unknown mechanism of action, but it is thought to work by enhancing the serotonergic activity in the central nervous system (CNS). It decreases inflammatory mediator release and normalizes trophic and metabolic support during neuron inflammation, which is linked to major depression. It also works as a 5HT2 receptor antagonist, which results in a sedative effect for sleep.

How to use

Read the medication guide or information leaflet that comes with this product first. Avoid using any antidepressant medication without fully understanding the drug information and precautions written in the guide. If you need further medical advice on your condition or have questions on the effects of this drug, you may ask your doctor or pharmacist.

Take the tablet orally. This is usually prescribed once or twice daily, depending on the advice of your physician. This should be taken with a meal or snack. It is also best to take a dose at bedtime. Swallow the medication and drink a glass of water thereafter.

Remember to take this drug regularly and as directed to achieve full benefits. Create a dosing regimen to avoid missing a dose. Do not alter your dosing as it is based on your response to medication and medical condition. Also, do not stop taking Desyrel to avoid withdrawal and worsening conditions. Some withdrawal symptoms are trouble sleeping or insomnia, anxiety, and agitation.

Desyrel Side Effects

Common side effects:

  • Nausea
  • Dizziness
  • Headache
  • Drowsiness
  • Vomiting
  • Tiredness
  • Dry mouth
  • Bad taste in the mouth
  • Blurred vision
  • Weight changes
  • Constipation
  • Low sex drive

Mostly, the side effects brought about by this drug are mild and may go away on their own. If the adverse reactions become worse or persist, you may have to hold Desyrel and call your doctor or any healthcare professional. Further, you should report severe side effects, such as:

  • Shaking or tremors
  • Nightmares
  • Problems urinating
  • Blood in the urine
  • Ringing in the ears
  • Shortness of breath
  • Abdominal pain
  • Chest pain
  • Fainting
  • Seizures
  • Irregular heartbeat
  • Eye pain
  • Widened pupils
  • Vision changes
  • Signs of infection (persistent sore throat, chills, fever)
  • Symptoms of serotonin syndrome (palpitations, severe vomiting, hallucinations, muscle twitching, loss of coordination, unexplained fever, agitation)

This is not a full or complete guide to the side effects of Desyrel.

Precautions when using Desyrel

Before you start to use this atypical antidepressant, you should disclose your complete medical history to your physician. This includes any history of suicide attempts, bipolar disorder, heart disease, kidney problems, liver disorders, blood pressure abnormalities, and glaucoma. Certain conditions may directly impact how your body will respond to Desyrel. Moreover, you should discuss the prescription drugs, nonprescription drugs, and herbal products (i.e., St. John’s Wort) you are taking, for they could have drug interactions with this SSRI.

Always lookout for an allergic reaction while taking this prescription drug. Do not take this tablet if you have a known allergy to trazodone, nefazodone, or any inactive ingredients it may contain. Signs of hypersensitivity are severe dizziness, swelling of the face and neck, skin rashes, hives, and breathing difficulty. If this occurs, immediately discontinue this antidepressant and seek emergency medical help.

This SSRI may cause QT prolongation, which could be considered a medical emergency. Watch out for signs like severe dizziness, fainting, palpitations, or any heartbeat irregularities. To avoid this, stay hydrated and do not take any diuretics. You should also be monitored for low levels of potassium and magnesium because they could also trigger QT prolongation.

Among the adverse effects of this oral drug are dizziness, drowsiness, and blurred vision. This could be triggered or worsened by alcohol. Limit your alcohol consumption, or avoid it, if possible. You should also practice extreme caution when doing activities that require alertness and clear vision, like driving and using machinery.

People taking this drug should continually be monitored for suicidal ideations. Some of the warning signs of suicide include social withdrawal, talking about dying, changes in sleep patterns, giving away important belongings, and changes in behavior. Alert your local suicide hotline if you notice these signs.

Pregnant or breastfeeding moms should take this oral antidepressant only when clearly needed. Always remember that potential benefits must be greater than the potential risks.

Frequently Asked Questions

Is this medication a psychotropic drug?

No, this medication is an atypical antidepressant.

How long will it take for Desyrel to improve my symptoms?

It may take one week to one month for this drug to improve your symptoms.

Can I take Desyrel for sleep problems?

Although trazodone is only approved to treat depression, it is also being prescribed as a sleep aid, especially for insomnia.

Does this medication cause hair loss?

Hair loss is not directly linked to this oral medication.

How much does Desyrel cost?

You may check for the prices of trazodone from this page.

Brand Name:


Scientific Name:


Other Names:

Trazodone FC, Trazodone HCL, Trazodone HCL FC


50mg, 100mg, 150mg

Quantities Available:

90, 100


Scored Tablet, Tablet

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Desyrel (Trazodone). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Desyrel (Trazodone).