Simbrinza Opthalmic Suspension (Brinzolamide/Brimonidine) from Maple Leaf Medications.

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Formulation : Opthalmic Suspension
Drug Name Dosage Quantity Price Buy Now
Simbrinza Opthalmic Suspension 1/0.2% 5mL $44.00 Add To Cart
Simbrinza Opthalmic Suspension 1/0.2% 10mL $72.00 Add To Cart
Simbrinza Opthalmic Suspension 1/0.2% 15mL $102.10 Add To Cart
Simbrinza Opthalmic Suspension
Dosage: 1/0.2%
Quantity: 5mL
Price: $44.00
Simbrinza Opthalmic Suspension
Dosage: 1/0.2%
Quantity: 10mL
Price: $72.00
Simbrinza Opthalmic Suspension
Dosage: 1/0.2%
Quantity: 15mL
Price: $102.10

What is Simbrinza Ophthalmic Suspension used for? 

This eye solution is used to help lower pressure in the eyes caused by glaucoma or ocular hypertension. Its active ingredients are brinzolamide, a carbonic anhydrase inhibitor, and brimonidine tartrate, an alpha-2 adrenergic receptor agonist.

Note that this eye medication helps prevent the risk of nerve damage, loss of vision, or blindness. 

How does Simbrinza Ophthalmic Suspension work? 

An imbalance between the inflow and outflow of aqueous humor happens when there is a rise in intraocular pressure (IOP). The imbalance in aqueous humor leads to high pressure inside the eye that can press against the optic nerve. Too much pressure in the eye can damage your optic nerve, and as a result, glaucoma develops.

When this eye medication is administered correctly, the active ingredients work for hand and hand in reducing pressure in the eyes. One component inhibits the carbonic anhydrase enzyme, responsible for sodium and fluid transport in your eyes. The mechanism of action of this medication reduces the secretion of aqueous humor, decreasing IOP.

Another effect of this drug is stimulating alpha receptors in the ciliary body. These receptors are responsible for releasing aqueous humor into the eye. The stimulation results in the constriction of the blood vessels to reduce aqueous humor, thereby lowering IOP.

Simbrinza Ophthalmic Suspension Dosage 

The dosage and frequency of this ophthalmic solution are different for every individual. It generally depends on the patient’s health status, the severity of their eye condition, age, and response to medication. This drug is available in optic suspension with a strength of 1/0.2%. 

The recommended dose for treating increased eye pressure is one drop into the affected eye three times a day. Make sure not to exceed the daily dose of this eye medication to prevent experiencing unwanted side effects. 

Directions on how to use Simbrinza Ophthalmic Suspension 

Before using this eye medication, read all medication instructions and information provided in the patient leaflet. Use the drug precisely as instructed and consult your healthcare provider, especially if you are unsure how to administer this eye suspension. 

Steps in using the eye suspension: 

  1. Before using this eye solution, shake the eye drops bottle well. If you have contact lenses, remove them before using these eye drops.
  2. Tilt your head backward, then gently pull down the lower lid to form a small pocket.
  3. Squeeze one drop of Simbrinza into the pocket and close your eyes for about two minutes.
  4. Press the inner side of your eye to prevent the medication from draining away.
  5. Repeat these steps with the other eye. 

Note that if you are using another ophthalmic solution, wait for at least five minutes before applying it. Make sure that the dropper tips and its other parts should not come in contact with your eyes to prevent contaminating the medication. 

Simbrinza Ophthalmic Suspension Side Effects 

The following are the most common side effects of this eye suspension that usually improve with time when your body gets used to the medication: 

  • Medication reaction in the treated eye
  • Eye stinging
  • Eye burning
  • Eye discomfort
  • Temporary blurring of vision
  • Dry eyes
  • Eye redness
  • Dry mouth
  • Unusual taste
  • Dizziness
  • Drowsiness
  • Fatigue
  • Headache 

Notify your doctor immediately if any of the side effects of this eye suspension worsen over time or if you develop any of the following adverse reactions: 

  • Allergic reaction
  • Hives
  • Swelling (face and lips)
  • Throat stiffness
  • Trouble breathing
  • Poor blood flow (brain, heart, or hands and feet) 

Note that this is not a complete list of the health implications related to this eye medication. Talk to your doctor for added information about other unwanted side effects. 

Simbrinza Ophthalmic Suspension Precautions 

Before using this eye medication, inform your doctor about your medical history, especially if you have circulation conditions, heart problems, liver diseases, or kidney disorders. Also, tell your physician if you have hypertension or depression, as this will help them decide if this optic drug is appropriate for you.

Do not use this medicine if you have a known allergy to Simbrinza, sulfa drugs, or other ingredients. This eye suspension may cause allergic reactions, so look out for allergic reactions.

Use caution when driving, operating machinery, or performing other hazardous activities, as this eye medication can cause drowsiness, dizziness, and blurred vision. 

Discontinue using eye medication if you experience blurred vision, eye pain, or eye redness, among other glaucoma symptoms. Call your doctor immediately when these symptoms develop. 

Keep this eye medication out of reach of the children and store it safely away from heat, moisture, and direct sunlight.

How much does Simbrinza Ophthalmic Suspension cost in Canada? 

The price of this eye medication is relatively reasonable, knowing how effective this drug is.

Maple Leaf Meds is offering a different quantity of this suspension. Check our pricing details at the top of this description and buy this drug at conveniently with ease and confidence.

FAQs about Simbrinza Ophthalmic Suspension 

Is Simbrinza a beta-blocker medication? 

No. This medication combines carbonic anhydrase inhibitors and alpha-2 adrenergic receptor agonists.

Is Simbrinza safe to use during pregnancy? 

The components of this medication can cross the placenta, which means a developing fetus can be exposed to it. Moreover, it is not known if this eye medication is safe to use during pregnancy. Make sure that the benefit of using this eye medication outweighs the risks.

Is it safe to use Simbrinza with alcohol? 

Drinking alcohol and this eye medication together may be dangerous. Both components may cause you to have slowed breathing and decreased heart rate.

Is it safe to use Simbrinza while wearing a contact lens? 

Before using this eye medication, make sure to remove your contact lenses. You can put your contacts back in after 15 minutes, as this medication can cause permanent staining in your eye drops.

Is it safe to use Simbrinza for young children? 

This eye medication is safe for children two years old and above. For children two years old and below, consult your doctor for other eye medications appropriate for your child. 




Brand Name:

Simbrinza Opthalmic Suspension

Scientific Name:


Other Names:




Quantities Available:

5mL, 10mL, 15mL


Opthalmic Suspension

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Simbrinza Opthalmic Suspension (Brinzolamide/Brimonidine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Simbrinza Opthalmic Suspension (Brinzolamide/Brimonidine).